Mindfulness Meditation Alleviates Fibromyalgia Symptoms in Women: Results of a Randomized Clinical Trial
Mindfulness Meditation Alleviates Fibromyalgia Symptoms in Women: Results of a Randomized Clinical Trial
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DOI：
10.1007/s12160-014-9665-0
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发表时间：
2015-06-01
影响因子：
3.8
通讯作者：
Sephton, Sandra E.
中科院分区：
文献类型：
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作者：
Cash, Elizabeth;Salmon, Paul;Sephton, Sandra E.
最近的几篇综述评估了正念减压疗法（MBSR）在纤维肌痛患者中的疗效，并得出结论，应该进行更多的研究来测试其对心理和生理功能的影响。我们在女性纤维肌痛患者中进行了一项随机前瞻性试验，研究MBSR对感知压力、疼痛、睡眠质量、疲劳、症状严重程度、和唾液皮质醇进行了测试，在治疗组（n = 51）与候补名单控制参与者（n = 40）使用的数据在基线，程序后，和2个月follow.Analyses显示，正念减压疗法显着减少感知压力，睡眠障碍，症状的严重程度，与收益保持在后续。随访时更多的家庭实践与症状严重程度降低相关。正念减压疗法并没有显著改变疼痛、身体功能或皮质醇水平，但改善了纤维肌痛的一些主要症状，并减轻了主观疾病负担。正念减压疗法对生理应激反应的影响有待进一步研究。这些结果支持使用正念减压疗法作为纤维肌痛女性患者的补充治疗（ISRCTN：34628811）。
Several recent reviews have evaluated evidence on the efficacy of Mindfulness-Based Stress Reduction (MBSR) among fibromyalgia sufferers, and concluded that more research should test effects on both psychological and physiological functioning.We conducted a randomized prospective trial of MBSR among female fibromyalgia patients.Effects on perceived stress, pain, sleep quality, fatigue, symptom severity, and salivary cortisol were tested in treatment (n = 51) versus wait-list control participants (n = 40) using data at baseline, post-program, and 2-month follow-up.Analyses revealed that MBSR significantly reduced perceived stress, sleep disturbance, and symptom severity, with gains maintained at follow-up. Greater home practice at follow-up was associated with reduced symptom severity. MBSR did not significantly alter pain, physical functioning, or cortisol profiles.MBSR ameliorated some of the major symptoms of fibromyalgia and reduced subjective illness burden. Further exploration of MBSR effects on physiological stress responses is warranted. These results support use of MBSR as a complementary treatment for women with fibromyalgia (ISRCTN: 34628811).