High level of novelty under the hood of convergent evolution
High level of novelty under the hood of convergent evolution
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DOI：
10.1126/science.ade0004
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发表时间：
2023-03-10
期刊：
影响因子：
56.9
通讯作者：
Papa, Riccardo
中科院分区：
文献类型：
--
作者：
Belleghem, Steven M. Van;Ruggieri, Angelo A.;Papa, Riccardo
很少有人知道在何种程度上物种使用同源调控架构，以实现表型收敛。通过表征发育中的翅膀组织中的染色质可及性和基因表达，我们比较了一对拟态蝴蝶物种之间趋同的调控结构。虽然少数的颜色图案基因被称为参与他们的收敛，我们的数据表明，不同的突变路径的基础上整合这些基因到翅膀图案的发展。这是由一个大部分的可访问的染色质是专有的每个物种，包括从头谱系特异性进化的模块化的optix增强子的支持。这些发现可能是由一个高水平的发展漂移和进化的偶然性，发生在模仿的独立进化。
Little is known about the extent to which species use homologous regulatory architectures to achieve phenotypic convergence. By characterizing chromatin accessibility and gene expression in developing wing tissues, we compared the regulatory architecture of convergence between a pair of mimetic butterfly species. Although a handful of color pattern genes are known to be involved in their convergence, our data suggest that different mutational paths underlie the integration of these genes into wing pattern development. This is supported by a large fraction of accessible chromatin being exclusive to each species, including the de novo lineage-specific evolution of a modular optix enhancer. These findings may be explained by a high level of developmental drift and evolutionary contingency that occurs during the independent evolution of mimicry.