Diffusion-weighted images of the liver: Comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide

Diffusion-weighted images of the liver: Comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide
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DOI:
10.1002/jmri.20346
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发表时间:
2005-06-01
影响因子:
4.4
通讯作者:
Takizawa, O
Takizawa, O
中科院分区:
医学2区
文献类型:
--
作者:
Naganawa, S;Sato, C;Takizawa, O

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目的:探讨超顺磁氧化铁(SPIO)可提高肝脏弥散加权图像(DWI)对恶性病变的识别能力。材料与方法:采用平行显像技术比较6例疑似1型肝恶性病变患者在1.5 Tesla时spio前后肝脏DWI - 1的变化。结果:spio后DWI显示恶性病变与肝脏的噪比改善。此外,脾信号在spio后DWI上减弱,从而避免了脾和肝左叶在最大强度投影(MIP)上的重叠。结论:SPIO能提高DWI对肝脏恶性病变的识别。在DWI的MIP图像上,SPIO有助于减少脾脏信号在某些投影角度上对肝脏的重叠。(c) 2005 Wiley-Liss, Inc。
Purpose: To study the recognition of malignant lesions of the 1, liver on diffusion-weighted images (DWI) can be improved by the administration of superparamagnetic iron oxide (SPIO).Materials and Methods: Pre- and post-SPIO mediated DWI 1 of the liver was compared in six patients with suspected 1 malignant liver lesions at 1.5 Tesla using a parallel imaging technique.Results: Post-SPIO DWI showed improved contrast-to-noise ratio between malignant lesions and liver. Furthermore, the spleen signal was decreased on post-SPIO DWI, thus avoiding the overlap of the spleen and left lobe of the liver on maximum intensity projections (MIP).Conclusion: Recognition of malignant lesions of the liver was improved by SPIO on DWI. On MIP images of DWI, SPIO helped to decrease the overlap of spleen signal on the liver in some projection angles. (c) 2005 Wiley-Liss, Inc.