Viscoelastic shear properties of human vocal fold mucosa: Measurement methodology and empirical results
Viscoelastic shear properties of human vocal fold mucosa: Measurement methodology and empirical results
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DOI：
10.1121/1.427947
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发表时间：
1999-10-01
影响因子：
2.4
通讯作者：
Titze, IR
中科院分区：
文献类型：
--
作者：
Chan, RW;Titze, IR
采用粘弹性材料经验流变学表征的标准方法，测量了人声带粘膜组织（固有层表层）的粘弹性剪切特性。采用平行板旋转流变仪测量了粘弹性组织样品的剪切变形，该样品在两个刚性圆板之间以小振幅正弦振荡旋转。然后基于流变仪记录的剪切应力和应变，将样品的弹性和粘性剪切模量定量为振荡频率（0.01至15 Hz）的函数。数据来自15个切除的人喉（10个男性和5个女性）。结果表明，人声带粘膜的弹性剪切模量mu和阻尼比zeta在所观察的频率范围内相对恒定，而动态粘度eta随频率单调下降（即，剪切稀化）。观察到mu和eta的受试者间差异高达一个数量级，其中部分可能反映了年龄相关和性别相关的差异。一些分子的解释的研究结果进行了讨论。(C)1999年美国声学学会。[S0001-4966（99）03710-8]。
A standard method for the empirical rheological characterization of viscoelastic materials was adopted to measure the viscoelastic shear properties of human vocal-fold mucosal tissues (the superficial layer of lamina propria). A parallel-plate rotational rheometer was employed to measure shear deformation of viscoelastic tissue samples, which were deformed between two rigid circular plates rotating in small-amplitude sinusoidal oscillations. Elastic and viscous shear moduli of the samples were then quantified as a function of oscillation frequency (0.01 to 15 Hz) based on shear stresses and strains recorded by the rheometer. Data were obtained from 15 excised human larynges (10 male and 5 female). Results showed that the elastic shear modulus mu and the damping ratio zeta of human vocal-fold mucosa were relatively constant across the range of frequencies observed, while the dynamic viscosity eta decreased monotonically with frequency (i.e., shear thinning). Intersubject differences in mu and eta as large as an order of magnitude were observed, part of which may reflect age-related and gender-related differences. Some molecular interpretations of the findings are discussed. (C) 1999 Acoustical Society of America. [S0001-4966(99)03710-8].