NATURAL OUTCOMES OF STAGE-1, STAGE-2, STAGE-3, AND STAGE-4 IDIOPATHIC MACULAR HOLES
NATURAL OUTCOMES OF STAGE-1, STAGE-2, STAGE-3, AND STAGE-4 IDIOPATHIC MACULAR HOLES
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DOI：
10.1136/bjo.79.6.517
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发表时间：
1995-06-01
影响因子：
4.1
通讯作者：
TREMPE, CL
中科院分区：
文献类型：
--
作者：
HIKICHI, T;YOSHIDA, A;TREMPE, CL
目的：研究特发性黄斑裂孔不同阶段的自然转归。方法对154只不同阶段的特发性黄斑裂孔进行回顾性研究：第一期40只眼，2只眼，25只眼，3只眼(58只眼)，4只眼(31只眼)。结果在第一期黄斑裂孔的27只眼中，9只眼(33%)形成了全层黄斑孔。无一例玻璃体后脱离黄斑的1期病变发展为全层裂孔。在中位3年的随访期中，2期病变25只眼中21只眼(84%)，3期病变58只眼中32只眼(55%)，4期病变31只眼中5只眼(16%)发生黄斑裂孔扩大。在随访期内，12只眼(30%)、17只眼(68%)、17只眼(29%)、17只眼(29%)、4只眼(13%)的视力下降了两行或两行以上的Snellen等效线。
Aims-A study was carried out to ascertain the natural outcome of each stage of idiopathic macular bore.Methods-One hundred and fifty four eyes with different stages of idiopathic macular holes were retrospectively studied: stage 1 (40 eyes), 2 (25 eyes), 3 (58 eyes), and 4 (31 eyes).Results-Of 27 of 40 eyes with a stage 1 lesion with posterior vitreous attachment to the macula initially, nine (33%) eyes developed a full thickness macular hole. No stage 1 lesions with posterior vitreous separation from the macula initially progressed to full thickness holes. Twenty one (84%) of 25 eyes with a stage 2 lesion, 32 (55%) of 58 eyes with a stage 3 lesion, and five (16%) of 31 eyes with a stage 4 lesion underwent macular hole enlargement during the median follow up period of 3 years. Visual acuity decreased two or more lines of Snellen equivalent during the follow up period in 12 (30%) eyes with a stage 1 lesion, 17 (68%) eyes with a stage 2 lesion, 17 (29%) eyes with a stage 3 lesion, and four (13%) eyes with a stage 4 lesion, The percentage was significantly higher in eyes with stage 2 lesions than the other stages (p