Functional MRI in human somatosensory cortex activated by touching textured surfaces.
Functional MRI in human somatosensory cortex activated by touching textured surfaces.
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通过触摸纹理表面激活人体体感皮层的功能性 MRI。
DOI：
10.1002/jmri.1880060402
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Burton,H
中科院分区：
文献类型：
--
作者：
Lin,W;Kuppusamy,K;Haacke,EM;Burton,H
MRI显示，在涉及指尖纹理表面刺激的方案中，人体体感觉皮层的激活灶。采用二维T2加权梯度回波序列获取图像。成像方案包括在受试者进行特定的触觉刺激范式（激活扫描）或休息时获取图像。使用三种不同的范例来产生功能激活，使用纹理表面摩擦一只手的指尖。首先，只有在激活扫描期间，一只手拿着纹理表面摩擦另一只手的指尖，才能产生运动感觉激活。其次，握住纹理表面的手在整个实验过程中都在移动，但只有在激活扫描期间才接触到另一只手的指尖。第三，在整个研究过程中，受试者都保持静止，而在激活扫描期间，研究人员在受试者的指尖上摩擦有纹理的表面。使用互相关方案对图像进行后处理。结果显示，在中央沟、中央后沟和前额叶皮层附近有多个运动感觉激活灶。
MRI revealed activation foci in human somatosensory cortex during protocols involving stimulation of the fingertips with a textured surface. A 2D T2*‐weighted gradient echo sequence was used to acquire images. The imaging protocol included acquiring images while subjects performed specific tactile stimulation paradigms (activation scans) or rested. Three different paradigms were used to produce functional activation using a textured surface to rub the fingertips of one hand. First, motor sensory activation was produced by rubbing the textured surface held in one hand against the fingertips of the opposite hand only during the activation scans. Second, the hand holding the textured surface moved throughout the experiment but touched the fingertips of the opposite hand only during the activation scans. Third, subjects remained still in the magnet throughout the entire study while an investigator rubbed the textured surface against the subjects' fingertips during the activation scans. Images were postprocessed using a cross‐correlation scheme. The results revealed multiple foci of motor sensory activation near the central sulcus, postcentral sulcus, and prefrontal cortex.