Serotypes of Ureaplasma urealyticum Isolated from Patients with Nongonococcal Urethritis and Gonorrhea and from Asymptomatic Urethral Carriers
Serotypes of Ureaplasma urealyticum Isolated from Patients with Nongonococcal Urethritis and Gonorrhea and from Asymptomatic Urethral Carriers
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从非淋菌性尿道炎和淋病患者以及无症状尿道带菌者中分离出解脲支原体血清型
DOI：
10.1097/00007435-198510000-00010
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发表时间：
1985
影响因子：
3.1
通讯作者：
M. Lazar
中科院分区：
文献类型：
--
作者：
E. Cračea;S. Constantinescu;M. Lazar
用标准解脲脲原体抗血清（血清型1 - 8）通过生长抑制试验对从112例非淋菌性尿道炎患者、17例淋病患者以及33例无症状携带者（对照）的尿道标本中分离出的解脲脲原体菌株进行检测。在非淋菌性尿道炎患者中有36.6%、淋病患者中有29.4%以及对照中有21.2%出现了一种以上血清型（2 - 4种）的情况。最常恢复的血清型在非淋菌性尿道炎患者中为血清型4（57.1%），在淋病患者和对照中为血清型2（分别为35.2%和36.3%）。非淋菌性尿道炎患者和对照之间血清型4的频率差异具有统计学意义（P＜0.001）。用血清型9和10的抗血清对来自非淋菌性尿道炎患者和对照的无法分型的菌株（分别为17.8%和21.2%）进行额外的血清分型，发现了3株血清型9的菌株。结果表明，在解脲脲原体引起的生殖器感染的流行病学和传播性研究中，有必要对解脲脲原体进行血清分型。
Ureaplasma urealyticum strains isolated from urethral specimens of 112 patients with nongonococcal urethritis, 17 with gonorrhea, and 33 asymptomatic carriers (controls) were tested by the growth-inhibition test with standard ureaplasma antisera (serotypes 1-8). Cases with more than one serotype (two to four types) were encountered in 36.6% of patients with nongonococcal urethritis, 29.4% of those with gonorrhea, and 21.2% of controls. The most frequently recovered serotypes were type 4 from patients with nongonococcal urethritis (57.1%) and type 2 from patients with gonorrhea and controls (35.2% and 36.3%, respectively). The difference in frequency of serotype 4 between patients with nongonococcal urethritis and controls was statistically significant (P less than .001). An additional serotyping with types 9 and 10 antisera of the nontypable strains from patients with nongonococcal urethritis and controls (17.8% and 21.2%, respectively) revealed three type-9 strains. The results show a need for utilization of serotyping of U. urealyticum in studies of the epidemiology and transmissibility of genital infections with U. urealyticum.