A transdiagnostic approach to conceptualizing depression across the perinatal period in a high-risk sample.
A transdiagnostic approach to conceptualizing depression across the perinatal period in a high-risk sample.
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DOI：
10.1037/abn0000612
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发表时间：
2020-10
影响因子：
4.6
通讯作者：
Stowe ZN
中科院分区：
文献类型：
--
作者：
Cochran AL;Pingeton BC;Goodman SH;Laurent H;Rathouz PJ;Newport DJ;Stowe ZN
Clinical guidelines recommend assessing depression during pregnancy and postpartum but often overlook potential changes in symptoms across this developmental period. Such changes contribute to difficulties in conceptualizing maternal depression. This study aimed to situate depressive symptoms and related concerns (anxiety, stress, sleep) across the perinatal period within a transdiagnostic framework and to use this framework to better understand how depressive symptoms change across the perinatal period. First, items from seven symptom scales were a priori categorized into six transdiagnostic factors: four based on Research Domain Criteria (Loss, Potential Threat, Frustrative Nonreward, and Sleep-Wakefulness) and two based on the depression literature (Somatic and Coping symptoms). Second, using prospective data from women with a history of an affective disorder (n=657) in an observational study of neuropsychiatric illness, factor analyses were performed in seven periods (3 trimesters of pregnancy and 4 quarters of first year postpartum). For each period, a bi-factor model with six transdiagnostic factors and a general factor fit data better than models that combined or dropped a factor (P < 0.003). Except around delivery, item loadings and intercepts could be fixed between consecutive periods and still adequately fit data from both periods. Means of Sleep-Wakefulness and Somatic factors increased significantly from second to third trimester (P < 0.01), with trends reversing early postpartum. In conclusion, depressive symptoms and related concerns exhibit factor structures that are only partly congruent across the perinatal period. This conclusion suggests that greater attention to specific life phases is warranted in the conceptualization of depression during this time in women’s lives. Depression has enduring adverse consequences to both mother and offspring during pregnancy and in the postpartum period. This study identifies a transdiagnostic framework for describing depressive symptoms and related concerns (sleep, stress, anxiety) at various periods in pregnancy and postpartum. Findings support efforts to conceptualize depression in terms of specific life phases.
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DOI：
10.1039/p29880000031
发表时间：
1988-01-01
期刊：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
影响因子：
--
作者：
COHEN, Y;KLEIN, J;RABINOVITZ, M
通讯作者：
RABINOVITZ, M
影响因子：
--
作者：
Grote, Nancy K.;Bridge, Jeffrey A.;Gavin, Amelia R.;Melville, Jennifer L.;Iyengar, Satish;Katon, Wayne J.
通讯作者：
Katon, Wayne J.
影响因子：
7.4
作者：
Fox, Molly;Sandman, Curt A.;Glynn, Laura M.
通讯作者：
Glynn, Laura M.
影响因子：
7.2
作者：
通讯作者：
--
影响因子：
4.6
作者：
Greene, Ashley L.;Eaton, Nicholas R.;Kotov, Roman
通讯作者：
Kotov, Roman