Controlling cell division in yeast and animals: does size matter?

Controlling cell division in yeast and animals: does size matter?
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DOI:
10.1186/1475-4924-2-5
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发表时间:
2003
期刊:
影响因子:
--
通讯作者:
Edgar BA
Edgar BA
中科院分区:
其他
文献类型:
--
作者:
Grewal SS;Edgar BA

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在酵母中,细胞大小的检查点协调细胞生长和细胞周期进程。现在,有证据表明,这种检查点可能不存在于哺乳动物细胞中。这些发现突显了酵母细胞和动物细胞对细胞外信号的反应方式之间的一个重要差异。
In yeast, cell-size checkpoints coordinate cellular growth with cell-cycle progression. Now, evidence has been provided that such checkpoints probably do not exist in mammalian cells. These findings highlight an important difference between how yeast and animal cells proliferate in response to extracellular cues.