Electronic nicotine delivery systems: regulatory and safety challenges: Singapore perspective
Electronic nicotine delivery systems: regulatory and safety challenges: Singapore perspective
复制标题
DOI：
10.1136/tobaccocontrol-2012-050483
复制
发表时间：
2014-03-01
期刊：
影响因子：
5.2
通讯作者：
Yee, Shen Kuan
中科院分区：
文献类型：
--
作者：
Cheah, Nuan Ping;Chong, Norman Wee Lin;Yee, Shen Kuan
目的许多电子尼古丁输送系统（ENDS）作为更安全的烟草替代产品或有效的戒烟疗法上市。评估了ENDS样品的设计特征，包括尼古丁和二醇含量。这可能是有用的，在开发一个法律的框架，以处理ENDS. Methods识别尼古丁，甘油和丙二醇（PPG）的内容进行了使用气相色谱-质谱进行定量使用火焰离子化techniques. Results不同的尼古丁量被发现在ENDS墨盒，其中被标记为相同的浓度。发现笔芯的含尼古丁液体中存在PPG和甘油等化学品。ENDS的内容物和包装信息各不相同。有限的信息是可利用的尼古丁和其他化学物质的含量存在于各种ENDS sample.Conclusions在这项研究中测试的样品的基础上，许多包含误导性的信息产品成分。结果表明，ENDS测试卡片上分析的实际尼古丁含量与标签上的含量之间的一致性较差。这些发现引起了当前和潜在的娱乐用户或试图戒烟者的安全性和有效性问题。
Objective Many electronic nicotine delivery systems (ENDS) are marketed as safer tobacco alternative products or effective cessation therapies. ENDS samples were evaluated for design features, including nicotine and glycols content. This could be useful in developing a legal framework to handle ENDS.Methods Identification of the nicotine, glycerol and propylene glycol (PPG) contents was conducted using gas chromatography mass spectrometry with quantification performed using flame ionisation techniques.Results Varying nicotine amounts were found in ENDS cartridges which were labelled with the same concentration. Chemicals such as PPG and glycerol were found to be present in the nicotine-containing liquid of the cartridges. ENDS varied in their contents and packaging information. Limited information was available on the contents of nicotine and other chemicals present in a variety of ENDS sampled.Conclusions Based on samples tested in this study, many contain misleading information on product ingredients. The results show poor consistency between actual nicotine content analysed on ENDS cartridges and the amount labelled. These findings raise safety and efficacy concerns for current and would-be recreational users or those trying to quit smoking.