A finite element strategy to investigate the free expansion behaviour of a biodegradable polymeric stent
A finite element strategy to investigate the free expansion behaviour of a biodegradable polymeric stent
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DOI：
10.1016/j.jbiomech.2015.03.024
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发表时间：
2015-07-16
影响因子：
2.4
通讯作者：
De Beule, Matthieu
中科院分区：
文献类型：
--
作者：
Debusschere, Nic;Segers, Patrick;De Beule, Matthieu
生物可吸收支架代表了心血管血管成形术领域的一项有前途的技术发展，因为它们能够避免传统支架的长期副作用，例如支架内再狭窄、晚期支架血栓形成和疲劳引起的支柱断裂。事实证明，有限元模拟为支架的设计和机械分析提供了一种有用的研究工具。然而，可生物降解支架由于其过渡机械行为而带来了新的挑战。对于聚合物生物可降解支架，必须考虑粘塑性效应。本文提出了一种使用隐式有限元求解器分析聚合物生物可吸收支架机械行为的方法。作为一个例子，我们研究了市售的生物可吸收支架的机械行为。我们研究了由于支架材料的粘弹性特性，球囊展开速率如何影响支架的机械完整性。 (C) 2015 Elsevier Ltd. 保留所有权利。
Bioresorbable stents represent a promising technological development within the field of cardiovascular angioplasty because of their ability to avoid long-term side effects of conventional stents such as in-stent restenosis, late stent thrombosis and fatigue induced strut fracture. Finite element simulations have proven to present a useful research tool for the design and mechanical analysis of stents. However, biodegradable stents pose new challenges because of their transitional mechanical behaviour. For polymeric biodegradable stents, viscoplastic effects have to be accounted for. This paper presents a method to analyse the mechanical behaviour of polymeric bioresorbable stents using an implicit finite-element solver. As an example, we investigate the mechanical behaviour of a commercially available bioresorbable stent. We examine how, due to the visco-elastic properties of the stent material, the balloon deployment rate influences the mechanical integrity of the stent. (C) 2015 Elsevier Ltd. All rights reserved.