Immunohistochemical localization and ontogenic development of prolactin-releasing peptide in the brain of the ovoviviparous fish species Poecilia reticulata (guppy)
Immunohistochemical localization and ontogenic development of prolactin-releasing peptide in the brain of the ovoviviparous fish species Poecilia reticulata (guppy)
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DOI：
10.1016/j.neulet.2006.10.011
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发表时间：
2007-02-21
影响因子：
2.5
通讯作者：
Yamamori, Kunio
中科院分区：
文献类型：
--
作者：
Amano, Masafumi;Oka, Yoshitaka;Yamamori, Kunio
为了更好地了解这种激素在硬骨鱼类中的作用，对卵胎生鱼类网状孔雀鱼（Poecilia reticulata，Guppy）脑中催乳素释放肽（Prolactin releasing peptide，PrRP）的免疫组织化学定位和个体发育进行了研究。在成年孔雀鱼，PrRP-免疫反应（IR）细胞体中检测到下丘脑的后部。在垂体中，少量的PrRP-IR纤维观察到相邻的催乳素细胞，而众多的PrRP-IR纤维检测到不仅在下丘脑，但也广泛地在整个大脑。PrRP-ir细胞体和催乳素细胞已经检测到出生当天在下丘脑和垂体，分别。随着鱼的发育，大脑中PrRP-ir纤维的数量增加。这些结果表明，PrRP参与脑中的神经调节，PrRP在孔雀鱼的早期发育中起着一定的生理作用。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
Immunohistochemical localization and ontogenic development of prolactin-releasing peptide (PrRP) in the brain of the ovoviviparous fish species Poecilia reticulata (guppy) were examined to gain a better understanding of this hormone in teleost fish. In adult guppies, PrRP-immunoreactive (ir) cell bodies were detected in the posterior part of the hypothalamus. In the pituitary, a small number of PrRP-ir fibers were observed adjacent to the prolactin cells, whereas numerous PrRP-ir fibers were detected not only in the hypothalamus but also widely throughout the brain. PrRP-ir cell bodies and prolactin cells were already detected on the birth day in the hypothalamus and pituitary, respectively. The number of PrRP-ir fibers in the brain increased as the fish developed. These results suggest that PrRP is involved in neuromodulation in the brain and that PrRP plays some physiological roles in the early development of the guppy. (c) 2006 Elsevier Ireland Ltd. All rights reserved.