Diabetes Alert Dogs (DADs): An assessment of accuracy and implications.
Diabetes Alert Dogs (DADs): An assessment of accuracy and implications.
复制标题
糖尿病警戒犬 (DAD)：准确性和影响的评估。
DOI：
10.1016/j.diabres.2017.09.009
复制
发表时间：
2017
影响因子：
5.1
通讯作者：
Shepard,JaclynA
中科院分区：
文献类型：
--
作者：
Gonder-Frederick,LindaA;Grabman,JesseH;Shepard,JaclynA
目的通过比较清醒和睡眠时间内记录的警报与连续葡萄糖监测（CGM）设备读数，测试糖尿病警报犬（DAD）的准确性。（7名1型糖尿病成人患者和7名1型糖尿病青年患者/父母）在≥6个月的时间内佩戴了盲态CGM器械，一周的时间内，同时记录DAD警报电子和纸质diares.ResultsDuring清醒时间，敏感性得分在参与者为低血糖事件和高血糖事件分别为35.9%和26.2%。DAD准确性差异很大，3/14只犬的表现在统计学上高于偶然性。糖尿病患者睡眠时间内的敏感性评分较低（低血糖事件为22.2%，高血糖事件为8.4%）。在睡眠时间内，DAD的准确性也是高度可变的，1/11的狗在统计学上表现得比偶然更好。变化率分析表明，DADs的绝对血糖水平，而不是葡萄糖level.ConclusionsIn这项研究中，大多数的DADs没有表现出准确的检测低血糖和高血糖事件的快速变化。然而，DAD之间的性能差异很大，需要进行额外的研究来检查导致这种差异的因素。此外，还需要更多的研究来调查DAD所有者报告的积极经验和临床结果与DAD准确性的混合研究结果之间的显著差距。
AimsTo test the accuracy of Diabetes Alert Dogs (DADs) by comparing recorded alerts to continuous glucose monitoring (CGM) device readings during waking and sleeping hours.Methods14 individuals (7 adults with type 1 diabetes and 7 youth with type 1 diabetes/parents) who owned DADs for ≥6 mos wore masked CGM devices over a several-week period while recording DAD alerts electronically and in paper diaries.ResultsDuring waking hours, sensitivity scores across participants were 35.9% for low BG events and 26.2% for high BG events. DAD accuracy was highly variable with 3/14 individual dogs performing statistically higher than chance. Sensitivity scores were lower during sleep hours of the person with diabetes (22.2% for low BG events and 8.4% for high BG events). DAD accuracy during sleeping hours was also highly variable, with 1/11 individual dogs performing statistically better than chance. Rate of change analyses indicated that DADs were responding to absolute BG level, rather than rapid shifts in glucose levels.ConclusionsIn this study the majority of DADs did not demonstrate accurate detection of low and high BG events. However, performance varied greatly across DADs and additional studies are needed to examine factors contributing to this variability. Additionally, more research is needed to investigate the significant gap between the positive experiences and clinical outcomes reported by DAD owners and the mixed research findings on DAD accuracy.