Association between added sugar intake and dental caries in Yup'ik children using a novel hair biomarker.
Association between added sugar intake and dental caries in Yup'ik children using a novel hair biomarker.
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DOI：
10.1186/s12903-015-0101-z
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发表时间：
2015-10-09
期刊：
影响因子：
2.9
通讯作者：
Lenaker D
中科院分区：
文献类型：
--
作者：
Chi DL;Hopkins S;O'Brien D;Mancl L;Orr E;Lenaker D
龋齿（蛀牙）是阿拉斯加原住民儿童的一个重大公共卫生问题。膳食添加糖被认为是主要风险因素之一。在这项横断面试点研究中，我们使用经过验证的基于头发的生物标记物来测量 6-17 岁阿拉斯加原住民尤皮克儿童的添加糖摄入量 (N = 51)。我们假设添加糖的摄入量与蛀牙呈正相关。进行了 66 项家长调查，从每个孩子身上采集了头发样本，并进行了牙科检查。使用碳和氮比率的线性组合从头发样本中测量添加糖摄入量（克/天）。我们使用具有稳健标准误差的线性和对数线性回归模型来检验我们的假设，即添加糖摄入量较高的儿童患龋齿的比例较高。龋齿表面的平均比例为 30.8%（标准差：23.2%）。基于头发生物标志物的添加糖摄入量与龋齿表面比例的绝对（6.4%；95% CI：1.2%、11.6%；P = .02）和相对增加（24.2%；95% CI：10.6%、39.4%；P < .01）相关。自我报告的含糖食品和饮料摄入量与蛀牙之间没有关联。在我们的尤皮克儿童样本中，通过头发生物标志物评估的添加糖摄入量与蛀牙显着呈正相关。自我报告的饮食措施与蛀牙无关。大多数添加糖来自家庭饮用的含糖果汁饮料。未来旨在改善阿拉斯加原住民儿童口腔健康的饮食干预措施应考虑使用客观生物标志物来评估和测量家庭添加糖摄入量的变化，特别是含糖果汁饮料。
Dental caries (tooth decay) is a significant public health problem in Alaska Native children. Dietary added sugars are considered one of the main risk factors. In this cross-sectional pilot study, we used a validated hair-based biomarker to measure added sugar intake in Alaska Native Yup’ik children ages 6–17 years (N = 51). We hypothesized that added sugar intake would be positively associated with tooth decay. A 66-item parent survey was administered, a hair sample was collected from each child, and a dental exam was conducted. Added sugar intake (grams/day) was measured from hair samples using a linear combination of carbon and nitrogen ratios. We used linear and log-linear regression models with robust standard errors to test our hypothesis that children with higher added sugar intake would have a higher proportion of carious tooth surfaces. The mean proportion of carious tooth surfaces was 30.8 % (standard deviation: 23.2 %). Hair biomarker-based added sugar intake was associated with absolute (6.4 %; 95 % CI: 1.2 %, 11.6 %; P = .02) and relative increases in the proportion of carious tooth surfaces (24.2 %; 95 % CI: 10.6 %, 39.4 %; P < .01). There were no associations between self-reported measures of sugar-sweetened food and beverage intake and tooth decay. Added sugar intake as assessed by hair biomarker was significantly and positively associated with tooth decay in our sample of Yup’ik children. Self-reported dietary measures were not associated tooth decay. Most added sugars were from sugar-sweetened fruit drinks consumed at home. Future dietary interventions aimed at improving the oral health of Alaska Native children should consider use of objective biomarkers to assess and measure changes in home-based added sugar intake, particularly sugar-sweetened fruit drinks.