TRPC5 and the path towards analgesic drug development.
TRPC5 and the path towards analgesic drug development.
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TRPC5 和镇痛药物开发之路。
DOI：
10.1016/j.tins.2021.06.010
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发表时间：
2021
影响因子：
15.9
通讯作者：
Denk F
中科院分区：
文献类型：
--
作者：
Denk F
Sadleret等人最近的一项研究强调了瞬时受体电位典型5（TRPC 5）作为治疗疼痛病症的潜在靶点。本文讨论了他们在镇痛药物开发背景下的发现，这是对抗阿片类药物危机和帮助数百万慢性疼痛患者所需的迫切追求。
A recent study by Sadleret al. highlights transient receptor potential canonical 5 (TRPC5) as a potential target for treating pain conditions. This article discusses their findings in the context of analgesic drug development, an urgent pursuit required to combat the opioid crisis and help millions of people with chronic pain.