The effectiveness of cervical screening: a population-based case-control study.

The effectiveness of cervical screening: a population-based case-control study.
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宫颈筛查的有效性:基于人群的病例对照研究。

DOI:
10.1016/0895-4356(88)90005-4
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发表时间:
1988
影响因子:
7.2
通讯作者:
Peter G. Vooijs
Peter G. Vooijs
中科院分区:
医学2区
文献类型:
--
作者:
Yolanda van der Graaf;G. A. Zielhuis;Petronella G. M. Peer;Peter G. Vooijs

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36名浸润性宫颈癌妇女的宫颈涂片病史与120名年龄匹配的对照进行了比较,这些对照来自当地登记办公室。在这些病例中,47%至少接受过一次筛查,而在对照组中,这一数字为68%。与从未接受过筛查的女性相比,至少接受过一次筛查的女性患浸润性宫颈癌的相对风险为0.32。最重要的混杂因素是初次性行为的年龄。然而,与其他研究相反的是,研究发现,初交年龄较小的女性接受筛查的频率更高。在校正了筛查与未筛查的第一次性行为年龄的相对风险后,相对风险变为0.22。当考虑到上一次涂片的间隔时间时,在2至5年前进行涂片的相对风险为0.18,而在5年前进行涂片的相对风险为0.30。这些结果支持了筛查在预防宫颈浸润性癌方面有效的假设。即使筛查间隔超过5年也能提供相当大的保护。
The cervical smear histories of 36 women with invasive cervical cancer were compared to those of 120 age-matched controls, drawn from local registrar's offices.Of the cases 47% were screened at least once, while for the controls this figure was 68%. The relative risk of getting invasive cervical cancer for women screened at least once compared to women who were never screened was 0.32. The most important confounding factor was age at first intercourse. Contrary to other studies however, it was found that women who were younger when having first intercourse were screened more often. After correcting the relative risk of screened vs unscreened for age at first intercourse, the relative risk became 0.22. When the length of the interval since the last smear was considered, the relative risk was 0.18 when the smear was made between 2 and 5 years earlier and 0.30 when this smear was made more than 5 years earlier. These results support the assumption that screening is effective in the prevention of invasive cancer of the uterine cervix. Even a screening interval of more than 5 years provides considerable protection.
宫颈癌流行病学中的饮食和吸烟。
DOI: --
发表时间: 1983
期刊: Journal of the National Cancer Institute
影响因子: --
作者:
Marshall,JR;Graham,S;Byers,T;Swanson,M;Brasure,J
通讯作者: Brasure,J