Effect of distracter preexposure on the reset of an internal clock
Effect of distracter preexposure on the reset of an internal clock
复制标题
DOI：
10.1016/j.beproc.2013.09.003
复制
发表时间：
2014-01-01
影响因子：
1.3
通讯作者：
Matthews, Alexander R.
中科院分区：
文献类型：
--
作者：
Buhusi, Catalin V.;Matthews, Alexander R.
定时信号中的干扰和不熟悉的事件（干扰物）会扰乱（延迟）人类和其他动物的定时。我们假设，重复暴露于刺激可能会减少其随后的时间中断属性。为了验证这一假设，大鼠在反向峰间期（RPI）程序中进行训练，其中黑暗计时试验由照明试验间间隔分开。然后将大鼠在黑暗（DARK组）或照明室（LIGHT组）中反复暴露于听觉刺激（噪音）;对照大鼠不暴露于噪音（NOVEL组）。之后，通过在（黑暗）RPI试验期间意外地呈现噪声来测试噪声的时间重置特性。NOVEL大鼠的噪声重置时间，但在DARK大鼠停止计时，表明预暴露减少了分心物的时间重置效果。然而，在LIGHT大鼠中，噪声在RPI试验早期出现时停止计时，但在后期出现时重置，这表明暴露于噪声中仅部分有效地覆盖其他相关变量，例如分心物位置。这些结果表明，干扰物预暴露的影响，内部时钟的复位取决于复杂的联想和时间的相互作用，需要进一步investigations.This文章是一个特殊的问题的一部分，题为：联想和时间的学习。(C)2013爱思唯尔有限公司版权所有。
Interruptions and unfamiliar events (distracters) during a timed signal disrupt (delay) timing in humans and other animals. We hypothesized that repeated exposure to a stimulus may reduce its subsequent time-disrupting properties. To test this hypothesis rats were trained in a reversed peak-interval (RPI) procedure, in which dark timing trials were separated by illuminated inter-trial intervals. Rats were then repeatedly exposed to an auditory stimulus (noise) in either dark (DARK group), or illuminated chambers (LIGHT group); control rats were not exposed to the noise (NOVEL group). Afterwards, the time-resetting properties of the noise were tested by presenting it unexpectedly during the (dark) RPI trials. The noise reset timing in NOVEL rats, but stopped timing in DARK rats, suggesting that preexposure reduces the time-resetting effects of distracters. However, in LIGHT rats, the noise stopped timing when the presented early in the RPI trial, but reset when presented late, suggesting that exposure to noise was only partly effective in overriding other relevant variables, such as distracter location. These results suggest that the effect of distracter preexposure on the reset of an internal clock depends on complex associative and temporal interactions which require further investigations.This article is part of a Special Issue entitled: Associative and Temporal Learning. (C) 2013 Elsevier B.V. All rights reserved.