Effects of exercise on S-IGA and URS in postmenopausal women.
Effects of exercise on S-IGA and URS in postmenopausal women.
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运动对绝经后女性 S-IGA 和 URS 的影响。
DOI：
10.1055/s-0032-1314817
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发表时间：
2013
影响因子：
2.5
通讯作者：
Davis,JE
中科院分区：
文献类型：
--
作者：
Sloan,CA;Engels,HJ;Fahlman,MM;Yarandi,HE;Davis,JE
32名绝经后妇女被随机分为16周的家庭步行计划组或对照组。在干预前后，每个受试者完成分级的最大跑台试验以确定VO 2 max，并收集静息唾液以测定唾液免疫球蛋白A水平。16周的步行计划导致最大摄氧量增加（+10.4%; p<0.01）。重复测量方差分析显示，在训练后，运动组唾液免疫球蛋白A的静息分泌率显著增加（+37.4%; p<0.05）。独立于研究组，在干预前后，唾液免疫球蛋白A的分泌率（− 32.3%）和唾液流量（− 29.3%）在急性最大运动后降低（p<0.05）。每周上呼吸道疾病日志显示，在整个干预期间，研究组之间的上呼吸道症状发生次数相同，每次发生的持续时间（对照组：5.3±1.5天;运动组：6.3±2.2天）相似。绝经后妇女的这些发现支持唾液免疫球蛋白A的分泌率和唾液流速在最大运动后立即降低。此外，16周的中等强度步行计划可以增加唾液免疫球蛋白A的分泌，而不影响上呼吸道炎症。
32 postmenopausal women were randomized to a 16-week home-based walking program or control group. Before and after the intervention, each subject completed a graded maximal treadmill test to establish VO2maxand resting saliva was collected to determine levels of salivary immunoglobulin A. The 16-week walking program resulted in an increase in VO2max(+10.4%; p<0.01). Repeated measures ANOVA revealed a marked increase in the resting secretion rate of salivary immunoglobulin A (+37.4%; p<0.05) in the exercise group following training. Independent of study group, both before and after the intervention, the secretion rate of salivary immunoglobulin A ( − 32.3%) and saliva flow rate (− 29.3%) were reduced following acute maximal exercise (p<0.05). Weekly upper respiratory symptomatology logs revealed that the number of incidences of upper respiratory symptoms throughout the intervention period were the same and the duration per incidence (control: 5.3±1.5 days; exercise: 6.3±2.2 days) were similar between study groups. These findings in postmenopausal women support that the secretion rate of salivary immunoglobulin A and saliva flow rate are reduced immediately following maximal exercise. Moreover, a 16-week moderate intense walking program can increase the secretion of salivary immunoglobulin A without affecting upper respiratory symptomatology.