MAFFT multiple sequence alignment software version 7: improvements in performance and usability.

MAFFT multiple sequence alignment software version 7: improvements in performance and usability.
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DOI:
10.1093/molbev/mst010
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发表时间:
2013-04
影响因子:
10.7
通讯作者:
Standley DM
Standley DM
中科院分区:
生物学1区
文献类型:
--
作者:
Katoh K;Standley DM

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我们报告的MAFFT多序列比对程序的重大更新。这个版本有几个新功能,包括在现有比对中添加未比对序列的选项,核苷酸比对方向的调整,约束比对和并行处理,这些都是在上一次重大更新后实现的。本报告展示了实际示例,以解释这些功能如何单独或组合工作。一些例子不正确的MAFFT对齐也表明,以澄清其局限性。我们讨论如何避免错位,以及我们正在努力克服这些限制。
We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update. This report shows actual examples to explain how these features work, alone and in combination. Some examples incorrectly aligned by MAFFT are also shown to clarify its limitations. We discuss how to avoid misalignments, and our ongoing efforts to overcome such limitations.