Headspace analysis with cryogenic focusing: A procedure for increasing the sensitivity of automated capillary headspace analysis
Headspace analysis with cryogenic focusing: A procedure for increasing the sensitivity of automated capillary headspace analysis
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低温聚焦顶空分析：提高自动毛细管顶空分析灵敏度的程序
DOI：
10.1007/bf02311877
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
P. Wylie
中科院分区：
文献类型：
--
作者：
P. Wylie
本文介绍了一种提高平衡顶空气相色谱灵敏度的简便方法。该技术涉及的0.32 mm fusedsilica毛细管柱，已耦合到填充柱注射端口的头部的顶部空间蒸气的低温聚焦。冷冻聚焦通过冷却GC烘箱自动完成，从而提高灵敏度和分辨率。使用这种简单的聚焦技术，不需要样品分裂，这使得灵敏度至少增加10倍。已经描述了多次顶空进样（MHI）技术，该技术允许在单次色谱运行开始时进行多次快速顶空进样。冷冻聚焦使注射叠加，从而进一步提高灵敏度。这些程序已被证明为牙膏和软饮料样品的风味和香气分析。
A convenient procedure has been described for enhancing the sensitivity of equilibrium headspace gas chromatography. The technique involves the cryogenic focusing of headspace vapors at the head of a 0.32 mm fusedsilica capillary column which has been coupled to a packed column injection port. Cryofocusing is accomplished automatically by cooling the GC oven and results in enhanced sensitivity with improved resolution. With this simple focusing technique no sample splitting is required which gives at least a 10-fold increase in sensitivity. A Multiple Headspace Injection (MHI) technique has been described which allows several rapid headspace injections to be made at the start of a single chromatographic run. Cryofocusing causes the injections to be superimposed, thus increasing the sensitivity even further. These procedures have been demonstrated for flavor and aroma analyses of toothpaste and soft drink samples.