Acute effects of air pollution on enteritis admissions in Xi'an, China
Acute effects of air pollution on enteritis admissions in Xi'an, China
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空气污染对中国西安市肠炎患者入院的严重影响
DOI：
10.1080/15287394.2016.1227006
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发表时间：
2016
影响因子：
2.6
通讯作者：
Cai Tong-Jian
中科院分区：
文献类型：
--
作者：
Xu Chen;Kan Hai-Dong;Fan Yan-Ni;Chen Ren-Jie;Liu Jiang-Hong;Li Ya-Fei;Zhang Yao;Ji Ai-Ling;Cai Tong-Jian
肠炎是一种常见的消化系统疾病，它与周围空气污染物的接触之间的相关性尚未得到全面研究。这项研究的目的是通过时间序列调查来确定西安市短期空气污染暴露与肠炎门诊就诊次数之间是否存在关联。获得了2013年1月1日至2015年12月31日的每日基线数据。采用过离散泊松广义加性模型分析空气污染物水平与肠炎发病频率之间的关系。总共确定了12,815次因肠炎而去医院就诊的门诊。颗粒物(PM)、PM2.5、二氧化氮(NO2)和二氧化硫(SO2)的平均浓度增加10微克/立方米，一氧化碳(CO)的平均浓度增加0.1毫克/立方米，与同时就诊的肠炎门诊次数显著增加相关，而臭氧(03)对肠炎临床就诊频率没有明显影响。双污染物模型与单污染物模型之间没有显著的正效应。滞后模型显示，最显著的反应发生在同时发生的日子。性别和年龄的混杂因素在观察中发挥了重要作用。综上所述，数据表明，空气污染可能导致肠炎发作的增加。
The correlation between enteritis, a common digestive disease, and exposure to ambient air pollutants has not been examined in a comprehensive manner. The aim of this study was to determine whether an association between short-term air pollution exposure and outpatient visits for enteritis in Xi’an, China, occurred using a time-series investigation. Daily baseline data from January 1, 2013, to December 31, 2015, were obtained. The overdispersed Poisson generalized additive model was used to analyze the association between air pollutant levels and frequency of enteritis. A total of 12,815 outpatient hospital visits for enteritis were identified. A 10-µg/m3increase in average concentrations of particulate matter (PM)10, PM2.5, nitrogen dioxide (NO2), and sulfur dioxide (SO2), and a 0.1-mg/m3rise of carbon monoxide (CO) were associated with a significantly elevated number of outpatient visits for enteritis on concurrent days, while ozone (O3) did not markedly affect the frequency of enteritis clinical visits. There were no significant positive effects between two-pollutant and single-pollutant models. Lag models showed that the most prominent responses occurred on concurrent days. Confounding factors of gender and age played a significant role in the observations. Taken together, data indicate that air pollution may result in enhanced occurrence of enteritis attack.