Treatment of stress urinary incontinence with a mobile app: factors associated with success.
Treatment of stress urinary incontinence with a mobile app: factors associated with success.
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DOI：
10.1007/s00192-017-3514-1
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发表时间：
2018-09
影响因子：
1.8
通讯作者：
Samuelsson E
中科院分区：
文献类型：
--
作者：
Nyström E;Asklund I;Sjöström M;Stenlund H;Samuelsson E
压力性尿失禁在女性中很常见。一线治疗包括盆底肌肉训练(PFMT)和生活方式建议，可以通过手机应用程序提供。基于APP的治疗的有效性已在随机对照试验(RCT)中得到证实。在这项研究中，我们旨在分析与成功治疗相关的因素。对随机对照试验数据的二次分析。在基线和3个月的随访中，参与者(n = 61)回答了关于症状、生活质量、背景和PFMT的问题。成功的定义是根据有效的患者总体改善印象问卷对病情进行评分为相当或非常好。可能与成功相关的因素用单变量Logistic回归分析；如果p <； 为0.20时，该因素进入根据年龄调整的多变量模型。然后逐步删除变量。在随访中，61名参与者中有34名(56%)表示他们的病情有很大或非常好的改善。3个因素与成功显著相关：对治疗的较高期望(优势比[OR]11.38，95%可信区间[CI]2.02-64.19)，体重控制(每公斤增加0.44，95%可信区间0.25-0.79)，以及自我评估的盆底肌力改善(OR 35.54，95%可信区间4.96-254.61)。这些因素加在一起，解释了成功变异性的61.4%(Nagelkerke R2)。这些结果表明，对这种治疗感兴趣并对其有较高期望的女性，基于APP的治疗效果更好。此外，这些发现还强调了加强盆底肌肉和提供生活方式建议的重要性。
Stress urinary incontinence is common among women. First-line treatment includes pelvic floor muscle training (PFMT) and lifestyle advice, which can be provided via a mobile app. The efficacy of app-based treatment has been demonstrated in a randomized controlled trial (RCT). In this study, we aimed to analyze factors associated with successful treatment. Secondary analysis of data from the RCT. At baseline and 3-month follow-up, participants (n = 61) answered questions about symptoms, quality of life, background, and PFMT. Success was defined as rating the condition as much or very much better according to the validated Patient Global Impression of Improvement questionnaire. Factors possibly associated with success were analyzed with univariate logistic regression; if p < 0.20, the factor was entered into a multivariate model that was adjusted for age. Variables were then removed stepwise. At follow-up, 34 out of 61 (56%) of participants stated that their condition was much or very much better. Three factors were significantly associated with success: higher expectations for treatment (odds ratio [OR] 11.38, 95% confidence interval [CI] 2.02–64.19), weight control (OR 0.44 per kg gained, 95% CI 0.25–0.79), and self-rated improvement of pelvic floor muscle strength (OR 35.54, 95% CI 4.96–254.61). Together, these factors accounted for 61.4% (Nagelkerke R2) of the variability in success. These results indicate that app-based treatment effects are better in women who are interested in and have high expectations of such treatment. Also, the findings underline the importance of strengthening the pelvic floor muscles and offering lifestyle advice.
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影响因子：
4.5
作者：
Sjostrom, Malin;Umefjord, Goran;Samuelsson, Eva
通讯作者：
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