Ytterbium - Doped Prussian blue: Fabrication, photothermal performance and antibacterial activity
Ytterbium - Doped Prussian blue: Fabrication, photothermal performance and antibacterial activity
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镱 – 掺杂普鲁士蓝：制造、光热性能和抗菌活性
DOI：
10.1016/j.inoche.2020.107821
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发表时间：
2020-04-01
影响因子：
3.8
通讯作者：
Wei, Shaohua
中科院分区：
文献类型：
--
作者：
Chen, Xin;Wu, Gang;Wei, Shaohua
近年来，光热疗法（PTT）在治疗细菌感染方面的应用受到了广泛的关注。普鲁士蓝（PB）是一种潜在的光热灭菌剂。PB中氰化键（- c N-）的电子密度对其PTT性能起决定性作用。同时，最近的研究表明，在镧系纳米材料芯上封装PB壳可以有效地提高其光热效率。因此，利用镧系与铁在改变氰化键电子密度上的差异，采用简单掺杂的方法制备了一系列掺杂PB纳米立方体的镧系离子，包括铒（Er3+）、镝（Dy3+）、铥（Tm3+）、镱（Yb3+）。其中Yb3+掺杂的PB （PB- yb）具有最佳的PTT性能。结构分析结果表明，PB-Yb中9%的Fe （Fe2+或Fe3+）被Yb3+取代，可以提高其电子密度，从而改善PTT性能。抗菌试验也验证了这一结论。以上结果证明，在铅中掺杂适当的镧系离子是改善其光热性能的一种简单有效的方法。
The application of photothermal therapy (PTT) to defeat bacterial infections has attracted great attention in the past years. Prussian blue (PB) is a potential photothermal agent in bacteria obliteration. The electron density of cyanide bonds (-C N-) in PB plays a decisive role on its PTT performance. Meanwhile, recent reports indicated that encapsulating PB shell on lanthanide nanomaterials core could effectively enhance its photothermal efficiency. Hence, a series of lanthanide ions, including erbium (Er3+), dysprosium (Dy3+), thulium (Tm3+), ytterbium (Yb3+), doped PB nanocubes were fabricated by a simple doping method due to the differences between lanthanide and iron on changing electron density of cyanide bond. And the Yb3+ doped PB (PB-Yb) has the best PTT performance of all nanocubes. Structure analyzing results indicate that 9% Fe (Fe2+ or Fe3+) were replaced by Yb3+ in PB-Yb, which could raise its electron density to improve its PTT performance. And the antibacterial test also verified the conclusion. All above results proved that doping proper lanthanide ions into PB is a simple and effective way to improve its photothermal performance.