Prognostic performance of pretreatment systemic immune-inflammation index in women with epithelial ovarian cancer.
Prognostic performance of pretreatment systemic immune-inflammation index in women with epithelial ovarian cancer.
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DOI：
10.2144/fsoa-2023-0108
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发表时间：
2023-12
影响因子：
2.5
通讯作者：
Salako O
中科院分区：
文献类型：
--
作者：
Okunade KS;John-Olabode SO;Soibi-Harry AP;Okoro AC;Adejimi AA;Ademuyiwa IY;Osunwusi B;Adelabu H;Salako O
本研究调查了尼日利亚拉各斯的上皮性卵巢癌（EOC）患者的全身免疫炎症指数（SII）的预后表现。我们对2009年至2018年期间接受EOC治疗的91名女性的数据进行了二次分析。预处理SII和生存之间的关联进行了测试。治疗前SII大于610.2是无进展生存期降低的显著独立预测因子（HR = 2.68; 95%CI，1.17 - 6.09），而SII大于649.0是3年总生存期降低的显著独立预测因子（HR = 2.01; 95%CI，1.01 - 3.99）。这些结果表明，高SII可能是一个潜在的预后指标和有用的标记物，更密集的监测和设计个性化治疗的EOC患者。这项研究着眼于系统免疫炎症指数（SII）如何预测上皮性卵巢癌（EOC）患者的预后。为此，分析了2009年至2018年期间接受EOC治疗的91名女性的数据。该研究得出结论，当SII水平高于610.2和649.0时，分别与EOC进展更快和3年生存率降低的可能性更高有关。这表明，高SII可能是了解EOC如何进展以及EOC患者生存情况的有用预测因素。
This study investigated the prognostic performance of the systemic immune-inflammation index (SII) in patients with epithelial ovarian cancer (EOC) in Lagos, Nigeria. We performed a secondary analysis of the data of 91 women who had treatment for EOC between 2009 and 2018. The associations between pretreatment SII and survivals were tested. Pretreatment SII more than 610.2 was a significant independent predictor of reduced progression-free survival (HR = 2.68; 95% CI, 1.17 to 6.09) while SII greater than 649.0 was a significant independent predictor of reduced 3-year overall survival (HR = 2.01; 95% CI, 1.01 to 3.99). These findings suggest that high SII may be a potential prognostic indicator and useful marker for more intensive surveillance and design of personalized treatment in patients with EOC. This study looked at how the systemic immune-inflammation index (SII) can predict the outcomes of patients with epithelial ovarian cancer (EOC). To do this, the data of 91 women who received treatment for EOC between 2009 and 2018 were analyzed. The study concluded that when the SII level was higher than 610.2 and 649.0, it was linked to a higher likelihood of EOC progressing sooner and of reduced survival at the 3-year mark, respectively. This suggests that a high SII might be a useful predictor to understand how EOC could progress and how well patients with EOC might survive.
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DOI：
10.3390/diagnostics7010012
发表时间：
2017-03-02
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
Koshiyama M;Matsumura N;Konishi I
通讯作者：
Konishi I
影响因子：
0.9
作者：
Okunade KS;Dawodu O;Adenekan M;Nwogu CM;Awofeso O;Ugwu AO;Salako O;John-Olabode S;Olowoselu OF;Anorlu RI
通讯作者：
Anorlu RI
DOI：
10.1097/igc.0000000000000361
发表时间：
2015-03
期刊：
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
影响因子：
--
作者：
Rizzuto I;Stavraka C;Chatterjee J;Borley J;Hopkins TG;Gabra H;Ghaem-Maghami S;Huson L;Blagden SP
通讯作者：
Blagden SP
影响因子：
3.3
作者：
通讯作者：
--
影响因子：
3.7
作者：
KAPLAN, EL;MEIER, P
通讯作者：
MEIER, P