Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: a comprehensive review.

Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: a comprehensive review.
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DOI:
10.1186/s12968-016-0308-4
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发表时间:
2016-11-30
期刊:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子:
--
通讯作者:
Plein S
Plein S
中科院分区:
其他
文献类型:
--
作者:
Haaf P;Garg P;Messroghli DR;Broadbent DA;Greenwood JP;Plein S

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心血管磁共振越来越多地用于区分心肌病的病因。晚期钆增强(LGE)是心肌疤痕和局灶性纤维化非侵入性成像的参考标准,对于缺血性与非缺血性心肌病的鉴别诊断很有价值。弥漫性纤维化在LGE成像中可能未被发现。使用参数标测方法进行组织表征有可能检测和量化LGE无法评估的心肌结构中的局灶性和弥漫性改变。特别是天然和造影后T1映射显示出作为一种新的生物标志物的前景,以支持缺血性和非缺血性心肌病以及急性胸痛综合征患者的诊断,治疗和预后决策。此外,心肌随时间的变化可以用这种非侵入性组织表征方法纵向评估。
Cardiovascular Magnetic Resonance is increasingly used to differentiate the aetiology of cardiomyopathies. Late Gadolinium Enhancement (LGE) is the reference standard for non-invasive imaging of myocardial scar and focal fibrosis and is valuable in the differential diagnosis of ischaemic versus non-ischaemic cardiomyopathy. Diffuse fibrosis may go undetected on LGE imaging. Tissue characterisation with parametric mapping methods has the potential to detect and quantify both focal and diffuse alterations in myocardial structure not assessable by LGE. Native and post-contrast T1 mapping in particular has shown promise as a novel biomarker to support diagnostic, therapeutic and prognostic decision making in ischaemic and non-ischaemic cardiomyopathies as well as in patients with acute chest pain syndromes. Furthermore, changes in the myocardium over time may be assessed longitudinally with this non-invasive tissue characterisation method.
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