Systolic Right Ventricular Function in Preterm and Term Neonates: Reference Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) in 258 Patients and Calculation of Z-Score Values
Systolic Right Ventricular Function in Preterm and Term Neonates: Reference Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) in 258 Patients and Calculation of Z-Score Values
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DOI：
10.1159/000322006
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发表时间：
2011-01-01
期刊：
影响因子：
2.5
通讯作者：
Gamillscheg, Andreas
中科院分区：
文献类型：
--
作者：
Koestenberger, Martin;Nagel, Bert;Gamillscheg, Andreas
背景资料：三尖瓣环平面收缩期振幅（TAPSE）是一种超声心动图测量，用于评估成人和儿童的右心室收缩功能。目的：探讨早产儿和足月儿TAPSE与生长发育及出生体重的相关性，为建立TAPSE的参考值提供依据。研究方法：在一组258名早产和足月新生儿（年龄：妊娠25+0至40+6周，出生体重：530- 4，200 g）中进行了一项前瞻性研究。结果如下：TAPSE范围从妊娠第26周早产新生儿的平均0.44 cm（Z评分+/- 2：0.30-0.59 cm）至妊娠第41周足月新生儿的1.03 cm（Z评分+/- 2：0.85-1.21 cm）。TAPSE值在孕26 ~ 41周呈线性增加。TAPSE、孕周和体重密切相关：妊娠周- TAPSE的Pearson相关系数为0.93（p < 0.001），妊娠周-出生体重的Pearson相关系数为0.93（p < 0.001），出生体重的Pearson相关系数为0.89（p < 0.001）。女性和男性患者之间的正常TAPSE值无统计学显著差异（p = 0.987）。结论：计算TAPSE值的Z评分，并建立百分位数图表，作为将来在结构正常心脏和先天性心脏病的早产儿和足月新生儿中随时应用的参考数据。版权所有（C）2011 S. Karger AG，巴塞尔
Background: The tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults and children. Objective: We determined growth-and birth weight-related changes of TAPSE to establish reference values in preterm and term neonates. Methods: A prospective study was conducted in a group of 258 preterm and term neonates (age: 25+0 to 40+6 weeks of gestation, birth weight: 530-4,200 g). Results: The TAPSE ranged from a mean of 0.44 cm (Z-score +/- 2: 0.30-0.59 cm) in preterm neonates in the 26th week of gestation to 1.03 cm (Z-score +/- 2: 0.85-1.21 cm) in term neonates in the 41st week of gestation. The TAPSE values increased in a linear way from the 26th to 41st week of gestation. TAPSE, week of gestation and weight are strongly correlated: Pearson's correlation coefficient was 0.93 for week of gestation - TAPSE (p < 0.001), 0.93 for week of gestation - birth weight (p < 0.001), and 0.89 for birth weight TAPSE (p < 0.001). There was no statistically significant difference of normal TAPSE values between female and male patients (p = 0.987). Conclusion: Z-scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future. Copyright (C) 2011 S. Karger AG, Basel