Research Trends and Hotspots Analysis Related to Monocarboxylate Transporter 1: A Study Based on Bibliometric Analysis
Research Trends and Hotspots Analysis Related to Monocarboxylate Transporter 1: A Study Based on Bibliometric Analysis
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单羧酸转运蛋白相关研究动态与热点分析1：基于文献计量分析的研究
DOI：
10.3390/ijerph16071091
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发表时间：
2019-03
影响因子：
--
通讯作者：
Su Jianmei
中科院分区：
文献类型：
--
作者：
He Siyi;Zhao Yue;Fan Yongsheng;Zhao Xue;Yu Jun;Xie Jie;Wang Chunhong;Su Jianmei
背景：单羧酸转运蛋白1(MCT1)已被定义为肿瘤能量代谢的重要调节因子，但对MCT1的文献计量学分析研究较少。本研究旨在综合分析全球MCT1研究成果，探索近十年来的研究热点和前沿。方法：检索Web of Science核心文献数据库2008~2018年发表的论文及其文献信息。我们使用Microsoft Excel 2016来检测年发文量的趋势，并使用Citesspace V软件作为文献计量学方法来分析研究领域、国家、机构、作者、期刊、研究热点和研究前沿。结果：共查出851篇论文，并呈上升趋势。相关文献主要集中在肿瘤学领域。最多产的国家和机构分别是美国和民浩大学。巴尔塔扎是最多产的作家，而哈雷斯特拉普的共同引文量最高。在过去的十年中，MCT1中最热门的话题是缺氧、基因表达和CD147。这三个研究前沿课题分别是增殖、肿瘤细胞和耐药性。近年来，MCT1在人类肿瘤细胞中的特殊作用成为学者们关注的焦点。结论：MCT1研究的发展前景是可以预期的，研究人员应重视MCT1抑制剂作为抗癌或免疫抑制药物的临床意义以及耐药形成的可能性。
Background: Monocarboxylate transport protein 1 (MCT1) has been defined as a critical regulator in tumor energy metabolism, but bibliometric analysis of MCT1 research is rare. This study aimed to comprehensively analyze the global scientific output of MCT1 research and explore the hotspots and frontiers from the past decade. Methods: Publications and their literature information from 2008 to 2018 were retrieved from the Web of Science Core Collection database. We used Microsoft Excel 2016 to detect the trend of annual numbers of publications, and used Citespace V software as the bibliometric method to analyze the research areas, countries, institutions, authors, journals, research hotspots, and research frontiers. Results: A total of 851 publications were identified with an increasing trend. Relevant literature mainly focused on the field of oncology. The most prolific country and institution were the USA and University of Minho, respectively. Baltazar was the most productive author while Halestrap had the highest co-citations. The hottest topics in MCT1 were hypoxia, gene expression, and CD147 over the last decade. The three research frontier topics were proliferation, tumor cell, and resistance. The special role of MCT1 in human tumor cells has become the focus for scholars recently. Conclusion: The development prospects of MCT1 research could be expected and researchers should pay attention to the clinical significance of MCT1 inhibitors as anti-cancer or immunosuppressive drugs and the possibility of drug-resistance formation.
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DOI：
10.1016/j.bbadis.2013.08.009
发表时间：
2013-12
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Sánchez-Tena S;Vizán P;Dudeja PK;Centelles JJ;Cascante M
通讯作者：
Cascante M
DOI：
10.1042/bj3430281
发表时间：
1999-10
期刊：
The Biochemical journal
影响因子：
--
作者：
A. Halestrap;N. Price
通讯作者：
A. Halestrap;N. Price
影响因子：
--
作者：
Morais-Santos F;Granja S;Miranda-Gonçalves V;Moreira AH;Queirós S;Vilaça JL;Schmitt FC;Longatto-Filho A;Paredes J;Baltazar F;Pinheiro C
通讯作者：
Pinheiro C
DOI：
10.4161/cc.24092
发表时间：
2013-05-01
期刊：
Cell cycle (Georgetown, Tex.)
影响因子：
--
作者：
Curry JM;Tuluc M;Whitaker-Menezes D;Ames JA;Anantharaman A;Butera A;Leiby B;Cognetti DM;Sotgia F;Lisanti MP;Martinez-Outschoorn UE
通讯作者：
Martinez-Outschoorn UE
影响因子：
64.8
作者：
Fuenfschilling, Ursula;Supplie, Lotti M.;Mahad, Don;Boretius, Susann;Saab, Aiman S.;Edgar, Julia;Brinkmann, Bastian G.;Kassmann, Celia M.;Tzvetanova, Iva D.;Moebius, Wiebke;Diaz, Francisca;Meijer, Dies;Suter, Ueli;Hamprecht, Bernd;Sereda, Michael W.;Moraes, Carlos T.;Frahm, Jens;Goebbels, Sandra;Nave, Klaus-Armin
通讯作者：
Nave, Klaus-Armin