Changes in functional connectivity within the fronto-temporal brain network induced by regular and irregular Russian verb production.
Changes in functional connectivity within the fronto-temporal brain network induced by regular and irregular Russian verb production.
复制标题
DOI：
10.3389/fnhum.2015.00036
复制
发表时间：
2015
影响因子：
2.9
通讯作者：
Medvedev SV
中科院分区：
文献类型：
--
作者：
Kireev M;Slioussar N;Korotkov AD;Chernigovskaya TV;Medvedev SV
涉及复杂语言形式处理的大脑区域之间的功能连接在很大程度上尚未探索。贡献的辩论神经机制的基础上定期和不规则的曲折形态加工的心理词汇，我们进行了功能磁共振成像实验中，参与者产生的形式，从不同类型的俄语动词和名词，以及从nonce刺激。这些数据进行了全脑体素分析的功能连接的上下文相关的变化[所谓的心理生理相互作用（PPI）分析]。与先前报道的减法结果显示大脑区域之间的功能分离不同，PPI提供了补充信息，显示这些区域如何在特定任务中功能整合。到目前为止，PPI的屈折形态学的证据一直是稀缺的，只有可用于屈折贫困英语动词在同一个不同的判断任务。使用PPI在这里结合生产任务中的曲折丰富的语言，我们发现，左额下回（LIFG）和双边上级颞回（STG）之间的功能连接显着更大的规则真实的动词比不规则的。此外，我们观察到一个显着的正协方差之间的错误的数量不规则的真实的动词试验和增加之间的功能连接LIFG和右前扣带皮层在这些线索，相比，定期的。因此，我们的研究结果允许规律性和加工难度的影响之间的解离。这些结果，一方面，揭示了新的光LIFG双边STG语言相关的网络内的功能相互作用，另一方面，呼吁部分重新考虑以前的一些研究结果，同时强调功能颞额连接在复杂的形态过程中的作用。
Functional connectivity between brain areas involved in the processing of complex language forms remains largely unexplored. Contributing to the debate about neural mechanisms underlying regular and irregular inflectional morphology processing in the mental lexicon, we conducted an fMRI experiment in which participants generated forms from different types of Russian verbs and nouns as well as from nonce stimuli. The data were subjected to a whole brain voxel-wise analysis of context dependent changes in functional connectivity [the so-called psychophysiological interaction (PPI) analysis]. Unlike previously reported subtractive results that reveal functional segregation between brain areas, PPI provides complementary information showing how these areas are functionally integrated in a particular task. To date, PPI evidence on inflectional morphology has been scarce and only available for inflectionally impoverished English verbs in a same-different judgment task. Using PPI here in conjunction with a production task in an inflectionally rich language, we found that functional connectivity between the left inferior frontal gyrus (LIFG) and bilateral superior temporal gyri (STG) was significantly greater for regular real verbs than for irregular ones. Furthermore, we observed a significant positive covariance between the number of mistakes in irregular real verb trials and the increase in functional connectivity between the LIFG and the right anterior cingulate cortex in these trails, as compared to regular ones. Our results therefore allow for dissociation between regularity and processing difficulty effects. These results, on the one hand, shed new light on the functional interplay within the LIFG-bilateral STG language-related network and, on the other hand, call for partial reconsideration of some of the previous findings while stressing the role of functional temporo-frontal connectivity in complex morphological processes.
登录
查看更多内容
影响因子：
5.7
作者：
Friston, KJ;Zarahn, E;Dale, AM
通讯作者：
Dale, AM
影响因子：
2.5
作者：
Brown, Steven;Laird, Angela R.;Pfordresher, Peter Q.;Thelen, Sarah M.;Turkeltaub, Peter;Liotti, Mario
通讯作者：
Liotti, Mario
影响因子：
5.7
作者：
Cisler JM;Bush K;Steele JS
通讯作者：
Steele JS
影响因子：
2.5
作者：
Beretta, A;Campbell, C;Cao, Y
通讯作者：
Cao, Y
影响因子：
3.2
作者：
Desai, R;Conant, LL;Binder, JR
通讯作者：
Binder, JR