Mismatch negativity and behavioural discrimination in humans as a function of the magnitude of change in sound duration

Mismatch negativity and behavioural discrimination in humans as a function of the magnitude of change in sound duration
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DOI:
10.1016/s0304-3940(00)01344-6
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发表时间:
2000-08-25
影响因子:
2.5
通讯作者:
Näätänen, R
Näätänen, R
中科院分区:
医学4区
文献类型:
--
作者:
Jaramillo, M;Paavilainen, P;Näätänen, R

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本研究以反映感觉记忆的听觉事件相关电位(ERP)的一个成分--失配负波(MMN)为指标,探讨了人脑对持续时间变化的处理。向受试者呈现一系列重复的100 ms白色噪声脉冲串,其中偶尔出现持续时间偏差,持续时间为1、10或50 ms(递减)或110、150或200 ms(递增)。在一个单独的任务中,受试者被要求通过按下按钮来检测序列中的异常。MMN引起的刺激减量和增量和增加幅度的函数的偏离量从标准的持续时间,除了最短的,1毫秒的偏差。行为检测的MMN的反应,这表明MMN和行为措施的过程之间的联系。(C)2000爱思唯尔科学爱尔兰有限公司保留所有权利。
This study investigated how duration changes are processed in the human brain as indexed by the mismatch negativity (MMN), a component of the auditory event-related potential (ERP) reflecting sensory memory. Subjects were presented with sequences of repetitive 100-ms white noise bursts interspersed by occasional duration deviants which were 1, 10, or 50 ms (decrements) or 110, 150, or 200 ms (increments) in duration. In a separate task, subjects were asked to detect deviants within the sequence via a button-press. MMN was elicited by both stimulus decrements and increments and increased in amplitude as a function of the amount of deviation from the standard duration except for the shortest, 1-ms deviant. Behavioural detection paralleled the MMN responses, suggesting a link between the processes underlying MMN and behavioural measures. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.