Lateral Habenula Serves as a Potential Therapeutic Target for Neuropathic Pain
Lateral Habenula Serves as a Potential Therapeutic Target for Neuropathic Pain
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DOI：
10.1007/s12264-021-00728-2
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发表时间：
2021
影响因子：
5.6
通讯作者：
Shi-Hong Zhang
中科院分区：
文献类型：
--
作者：
Yu Du;Yu-Xing Wu;Fang Guo;Feng-Hui Qu;Ting-Ting Hu;Bei Tan;Yi Wang;Wei-Wei Hu;Zhong Chen;Shi-Hong Zhang
Neuropathic pain (NeuP) is known as a common and notorious neurological disease, characterized by spontaneous pain and evoked abnormal pain that includes hypersensitivity to external innocuous (allodynia) and noxious stimulation (hyperalgesia). Allodynia is especially torturous because gentle touch may trigger pain. The high incidence of resistance to common analgesics makes the clinical management of NeuP challenging. More research is urgently needed to better understand the mechanisms of NeuP and to develop new therapeutic strategies.
