In vivo application of short-lag spatial coherence imaging in human liver.

In vivo application of short-lag spatial coherence imaging in human liver.
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DOI:
10.1016/j.ultrasmedbio.2012.09.022
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发表时间:
2013-03
影响因子:
2.9
通讯作者:
Dahl, Jeremy J.
Dahl, Jeremy J.
中科院分区:
医学3区
文献类型:
--
作者:
Jakovljevic, Marko;Trahey, Gregg E.;Nelson, Rendon C.;Dahl, Jeremy J.

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我们介绍了一项患者研究的结果,以评估两种新的成像方法,即短时滞空间相干成像(SLSC)和谐波空间相干成像(HSCI)在活体肝脏环境中的性能。在外观上与B模式图像相似,SLSC和HSCI图像分别仅基于基波和谐波回波数据的空间相干性,而不依赖于回波幅度。SLSC和HSCI抑制非相干回波信号,因此倾向于减少杂波。17例患者的SLSC和HSCI图像显示,与匹配的B超相比,血管壁的轮廓更清晰,管腔内的杂乱被抑制,周围组织中的斑点减少。目标对比度和对比度噪声比(CNR)在基波B超和SLSC成像以及谐波B超和HSCI成像之间显示出统计学意义上的显著改善(在所有情况下P<0.01)。对比度和CNR的改善幅度随着B模式图像的整体质量降低而增加。质量差的基本B模式图像(其中图像质量分类基于对比度和CNR)在对比度和CNR方面都表现出最高的改善(对比度改善288%,CNR改善533%)。
We present the results of a patient study conducted to assess the performance of two novel imaging methods, namely Short-Lag Spatial Coherence (SLSC) and Harmonic Spatial Coherence Imaging (HSCI), in in vivo liver environment. Similar in appearance to the B-mode images, SLSC and HSCI images are based solely on the spatial coherence of fundamental and harmonic echo data, respectively, and do not depend on the echo magnitude. SLSC and HSCI suppress incoherent echo signals and thus tend to reduce clutter. The SLSC and HSCI images of 17 patients demonstrate sharper delineation of blood vessel walls, suppressed clutter inside the vessel lumen, and show reduced speckle in surrounding tissue compared to matched B-modes. Target contrast and contrast-to-noise ratio (CNR) show statistically significant improvements between fundamental B-mode and SLSC imaging and between harmonic B-mode and HSCI imaging (in all cases p < 0.01). The magnitude of improvement in contrast and CNR increases as the overall quality of B-mode images decreases. Poor quality fundamental B-mode images (where image quality classification is based on both contrast and CNR) exhibit the highest improvements in both contrast and CNR (288 % improvement in contrast and 533 % improvement in CNR).
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