Anodal tDCS of the lower limb M1 does not acutely affect clinical blood pressure and heart rate in healthy and post stroke individuals.
Anodal tDCS of the lower limb M1 does not acutely affect clinical blood pressure and heart rate in healthy and post stroke individuals.
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DOI：
10.15226/2374-6858/2/2/00118
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发表时间：
2015-01-01
期刊：
影响因子：
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通讯作者：
Madhavan, Sangeetha
中科院分区：
文献类型：
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作者：
Nguyen, Tai Tri;Ugwu, John;Madhavan, Sangeetha
经颅直流电刺激（tDCS）是一种非侵入性的大脑刺激技术，作为一种辅助方式来增强运动疗法效果的研究日益增多。尽管tDCS在认知、感觉和知觉方面的安全性已得到充分综述，但关于其对血压和心率影响的信息仍然有限。由于tDCS在很大程度上与中风康复联合使用，我们了解tDCS对中风人群自主神经功能的影响是很重要的。在这项回顾性研究中，我们通过对血压和心率的临床测量，检测了在健康个体和中风后个体中下肢运动皮层tDCS的急性效应。15分钟1毫安的阳极tDCS未引起血压或心率任何临床上可检测到的变化。这是第一项报告在健康个体和中风后个体中下肢M1区tDCS对心血管自主神经影响的研究。需要进一步的研究来检验在重复应用tDCS过程中这些安全效应是否保持不变。
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique increasingly investigated an adjunct modality to enhance the effects of motor therapy. Although the safety of tDCS in relation to cognition, sensation and perception has been well reviewed, there still exists limited information regarding its effects on blood pressure and heart rate. As tDCS is being largely used in conjunction with stroke rehabilitation, it is important that we understand the effects of tDCS on autonomic function in the stroke population. In this retrospective study, we examined the acute effects of tDCS of the lower limb motor cortex in healthy and post stroke individuals using clinical measurements of blood pressure and heart rate. Fifteen minutes of 1 mA anodal tDCS did not cause any clinically detectable changes in blood pressure or heart rate. This is the first study to report the cardiovascular autonomic effects of tDCS of the lower limb M1 in healthy and post stroke individuals. Further studies are needed to examine if these safety effects are preserved during repeated applications of tDCS.