Effects of Kurozu Moromi powder and Kurozu concentrated liquid on carbohydrate metabolism
Effects of Kurozu Moromi powder and Kurozu concentrated liquid on carbohydrate metabolism
复制标题
黑津醪粉和黑津浓缩液对碳水化合物代谢的影响
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
M. Fujii
中科院分区：
文献类型：
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作者：
M. Nagano;A. Fujii;Y. Aoyama;M. Kurita;M. Fujii
研究了黑津森味散和黑津浓缩液的体外和体内生理作用。在此之前，我们利用大鼠肠外翻的肠囊来评价黑津森味散和黑津浓缩液对葡萄糖的抑制作用。黑津森味散和黑津浓缩液对葡萄糖的肠道吸收有显著抑制作用。采用口服黑津森味散和黑津浓缩液对KKA小鼠的作用进行了评价。黑津森味散和黑津浓缩液连续饲喂30d显著降低KKA - y小鼠持续饲喂时的平均血糖、1,5-无水d -葡萄糖醇和血红蛋白a1c水平，单次口服黑津森味散和黑津浓缩液显著降低KKA - y小鼠蔗糖负荷后的平均曲线下面积。上述结果提示，摄入黑津森味散和黑津浓缩液可防止血糖升高。因此，每日摄入黑津森味散和黑津浓缩液可能有助于改善2型糖尿病。
Kurozu Moromi powder and Kurozu concentrated liquid was examined in vitro and in vivo for its physiological effects. Previously, the inhibitory effect of Kurozu Moromi powder and Kurozu concentrated liquid on glucose was evaluated using the everted gut sacs of the rat intestine. Kurozu Moromi powder and Kurozu concentrated liquid significantly suppressed the intestinal absorption in glucose. Kurozu Moromi powder and Kurozu concentrated liquid was evaluated in KKA y mice by oral administration. Kurozu Moromi powder and Kurozu concentrated liquid feeding for 30days significantly lowered the mean plasma glucose, 1,5-Anhydro-D-Glucitol and hemoglobin A 1c level of KKA y mice under fed continuations, and single oral administration of Kurozu Moromi powder and Kurozu concentrated liquid significantly lowered the mean area under the curve after sucrose loading in KKA y mice. These results suggest that intake of Kurozu Moromi powder and Kurozu concentrated liquid prevents the increase in blood glucose level. Consequently, daily intake of Kurozu Moromi powder and Kurozu concentrated liquid might be useful for improvement of type 2 diabetes mellitus.