Effects of physostigmine on pulse, blood pressure, and serum epinephrine levels.
Effects of physostigmine on pulse, blood pressure, and serum epinephrine levels.
复制标题
毒扁豆碱对脉搏、血压和血清肾上腺素水平的影响。
DOI：
10.1176/ajp.142.6.738
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Ziegler,M
中科院分区：
文献类型：
--
作者：
Janowsky,DS;Risch,SC;Huey,LY;Kennedy,B;Ziegler,M
在这项研究中，14名接受甲东莨菪碱预治疗的情感障碍患者输注毒扁豆碱，导致患者肾上腺素水平、脉率和血压显著增加，而且往往是深刻的增加。由于毒扁豆碱被实验性地用于治疗患有阿尔茨海默病的老年受试者，这些心血管效应可能具有临床重要性。
In this study, the infusion of physostigmine in 14 patients with affective disorder who were pretreated with methscopolamine caused significant and often profound increases in the patients' epinephrine levels, pulse rates, and blood pressure. Since physostigmine is being used experimentally in the treatment of elderly subjects who have Alzheimer's disease, these cardiovascular effects may have clinical importance.