Antioxidant Activities, Metabolic Profiling, Proximate Analysis, Mineral Nutrient Composition of Salvadora persica Fruit Unravel a Potential Functional Food and a Natural Source of Pharmaceuticals.
Antioxidant Activities, Metabolic Profiling, Proximate Analysis, Mineral Nutrient Composition of Salvadora persica Fruit Unravel a Potential Functional Food and a Natural Source of Pharmaceuticals.
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DOI：
10.3389/fphar.2017.00061
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发表时间：
2017
影响因子：
5.6
通讯作者：
Panda A
中科院分区：
文献类型：
--
作者：
Kumari A;Parida AK;Rangani J;Panda A
丹参是一种重要的药用植物，主要用于口腔卫生。然而，很少有人注意到这种植物的营养价值。本研究对桃果实的营养成分、矿质营养成分、氨基酸组成、代谢产物组成和抗氧化能力进行了研究。成熟果实中含有大量的糖类、矿质营养、类胡萝卜素、多酚和类黄酮类物质。用GC-MS对果实提取物的代谢谱进行分析，结果表明，果实提取物中含有22种代谢物，包括糖、糖醇、有机酸、有机碱和芳香二氧化硅化合物。已鉴定的代谢物先前已被报道具有潜在的抗氧化、抗菌、抗高血糖和抗肿瘤特性。GC-MS分析表明，桃果实中葡萄糖和吡喃葡萄糖含量较高(分别为247.62和42.90mgg-1FW)。果实提取物表现出明显较高的抗氧化性和清除ROS的能力，以及高含量的矿物质营养和必需氨基酸。高效液相色谱分析显示，人体健康代谢所需的必需和非必需氨基酸的存在。半胱氨酸的含量最高(733.69 mg，100g-1DW)。具体地说，与以前被报告为非常规食品来源的类似药用植物相比，与一些具有商业重要性的水果相比，桃树果实似乎是基本矿物质营养素、氨基酸、维生素(抗坏血酸和类胡萝卜素)和具有重要药用价值的代谢物的潜在来源，有助于满足健康人体对这些物质的推荐每日需求。这是首次报道了桃果实作为营养食品的重要性。本研究提供的数据表明，桃子可作为功能性食品或加工食品的补充剂，以减少弱势群体的营养缺乏。从桃果实中鉴定出的植物化学成分可作为药物制剂的天然来源。
Salvadora persica is a medicinally important plant mainly used in oral hygiene. However, little attention has been given towards the nutritional prominence of this plant. This study encloses the proximate and mineral nutrient contents, amino acid composition, metabolite profiling and antioxidant potential of S. persica fruit. The ripen fruit contained substantial amount of sugars, mineral nutrients, carotenoids, polyphenols and flavonoids. The metabolic profiling of the fruit extract by GC-MS revealed a total of 22 metabolites comprising of sugars, sugar alcohols, organic acids, organic base, and aromatic silica compound. The identified metabolites have been previously reported to have potential antioxidant, antimicrobial, anti-hyperglycemic, and antitumor properties. The GC-MS analysis indicated high glucose and glucopyranose (247.62 and 42.90 mg g-1 FW respectively) contents in fruit of S. persica. The fruit extract demonstrated a significantly higher antioxidant and ROS scavenging properties along with high contents of mineral nutrients and essential amino acids. HPLC analysis revealed presence of essential and non-essential amino acid required for healthy body metabolism. The cysteine was found to be in highest amount (733.69 mg 100 g-1 DW) among all amino acids quantified. Specifically, compared to similar medicinal plants, previously reported as a source of non-conventional food and with some of the commercially important fruits, S. persica fruit appears to be a potential source of essential mineral nutrients, amino acids, vitamins (ascorbic acid and carotenoid) and pharmaceutically important metabolites contributing towards fulfilling the recommended daily requirement of these for a healthy human being. This is the first report establishing importance of S. persica fruit as nutraceuticals. The data presented here proposed that fruit of S. persica may be used as functional food or reinvigorating ingredient for processed food to reduce deficiency of nutrients among the vulnerable population group. The phytochemicals identified from S. persica fruit may be used as natural source for pharmaceutical preparations.