Glucose tolerance predicts performance on tests of memory and cognition

Glucose tolerance predicts performance on tests of memory and cognition
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DOI:
10.1016/s0031-9384(00)00359-0
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发表时间:
2000-11-01
影响因子:
2.9
通讯作者:
Benton, D
Benton, D
中科院分区:
医学3区
文献类型:
--
作者:
Donohoe, RT;Benton, D

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考虑了控制血糖水平的能力影响记忆和认知的其他方面的假设。通过对 46 名年轻成年女性进行葡萄糖耐量试验 (GTT) 来测量控制血糖能力的个体差异。对一系列葡萄糖耐量测量值的因子分析产生了四个维度。一周后。吃完正常的早餐后,他们接受了记忆力、反应时间和警惕性的测试。血糖升高的速度(在 GTT 中达到最低点)与一周后测量的记忆力相关。在进行测试时,那些到达实验室时血糖水平较高的人在监测八盏灯而不是四盏、两盏或一盏灯时反应时间更快。这一发现被解释为证明较高水平的血糖特别会影响对大脑提出更高要求的任务。 (C) 2000 Elsevier Science Inc. 保留所有权利。
The hypothesis that the ability to control blood glucose levels influence memory and other aspects of cognition was considered. Individual differences in the ability to control blood glucose were measured by giving a glucose tolerance test (GTT) to 46 young adult females. A factor analysis of a series of measures of glucose tolerance produced four dimensions. A week later. having eaten their normal breakfast, they took tests of memory, reaction times and vigilance. The speed with which blood glucose increased, having its lowest point in the GTT, was associated with memory measured a week later. While performing the tests those with higher levels of blood glucose on arrival in the laboratory had quicker reaction times when monitoring eight but not four, two or one lamps. The finding was interpreted as demonstrating that higher levels of blood glucose specially influence tasks placing higher demands on the brain. (C) 2000 Elsevier Science Inc. All rights reserved.