In vitro prominent bone regeneration by release zinc ion from Zn-modified implant.
In vitro prominent bone regeneration by release zinc ion from Zn-modified implant.
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DOI：
10.1016/j.bbrc.2011.07.082
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发表时间：
2011-08
影响因子：
3.1
通讯作者：
K. Yusa;Osamu Yamamoto;M. Fukuda;S. Koyota;Yukio Koizumi;T. Sugiyama
中科院分区：
文献类型：
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作者：
K. Yusa;Osamu Yamamoto;M. Fukuda;S. Koyota;Yukio Koizumi;T. Sugiyama
用8-氨基喹啉衍生物共价修饰氧化铁磁性纳米粒子，制备了一种在pH 7.0水溶液中具有高灵敏度和选择性的Zn 2+荧光纳米传感器.通过物理化学方法对纳米传感器进行了充分的表征。该传感器可检测水溶液中的Zn ~（2+）离子，灵敏度为0.1μM，干扰金属离子不影响其选择性。MTT实验表明，该传感器无明显的细胞毒性。
Iron oxide magnetic nanoparticles were covalently modified by a fluorescent 8-aminoquinoline derivative and formed an optical sensor to be used as a highly sensitive and selective Zn2+ions fluorescent nanosensor in aqueous solution at pH 7.0. The nanosensor was sufficiently characterized by physicochemical methods. The sensor can detect Zn2+ions in aqueous solution with a submicromolar sensitivity of 0.1μM, and the interfering metal ions cannot influence its selectivity. MTT assay experiments indicated that the sensor showed no apparent cytotoxicity.