Effects of parental smoking on exercise systolic blood pressure in adolescents.
Effects of parental smoking on exercise systolic blood pressure in adolescents.
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DOI：
10.1161/jaha.115.001936
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发表时间：
2015-05-11
影响因子：
5.4
通讯作者：
Weisser B
中科院分区：
文献类型：
--
作者：
Hacke C;Weisser B
在成年人中，运动血压似乎比静息血压与心血管风险更密切相关;然而，关于家庭危险因素（包括吸烟习惯）对青少年运动血压影响的数据很少。在基尔EX.E.研究所对532名12 - 17岁（14.6±1.5岁）青少年进行了静息和运动时血压、父母吸烟和其他家族危险因素的调查。学习。使用标准化的次最大踏车测力计测试在1.5 W/kg体重下测定运动血压。平均静息血压为113.1±12.8/57.2±7.1 mm Hg，运动血压为149.9±19.8/54.2±8.6 mm Hg。父母吸烟增加了受试者的运动收缩压（+4.0 mm Hg，3.1至4.9; P=0.03），但未增加受试者的静息血压（根据年龄、性别、身高、体重指数百分位数、健身进行调整）。父母超重和家族性高血压与较高的静息和运动收缩压值有关，而与不活动的生活方式和父母教育水平低的关联仅与青少年运动期间的血压有关。家族危险因素对运动收缩压的累积效应比对静息血压的累积效应更明显。父母吸烟可能是高血压的一个新的危险因素，特别是在运动期间。此外，次极量运动试验中的收缩压与家族性危险因素的相关性比静息血压更密切，即使在青少年中也是如此。
In adults, exercise blood pressure seems to be more closely related to cardiovascular risk than resting blood pressure; however, few data are available on the effects of familial risk factors, including smoking habits, on exercise blood pressure in adolescents. Blood pressure at rest and during exercise, parental smoking, and other familial risk factors were investigated in 532 adolescents aged 12 to 17 years (14.6±1.5 years) in the Kiel EX.PRESS. (EXercise PRESSure) Study. Exercise blood pressure was determined at 1.5 W/kg body weight using a standardized submaximal cycle ergometer test. Mean resting blood pressure was 113.1±12.8/57.2±7.1 mm Hg, and exercise blood pressure was 149.9±19.8/54.2±8.6 mm Hg. Parental smoking increased exercise systolic blood pressure (+4.0 mm Hg, 3.1 to 4.9; P=0.03) but not resting blood pressure of the subjects (adjusted for age, sex, height, body mass index percentile, fitness). Parental overweight and familial hypertension were related to both higher resting and exercise systolic blood pressure values, whereas associations with an inactive lifestyle and a low educational level of the parents were found only with adolescents’ blood pressure during exercise. The cumulative effect of familial risk factors on exercise systolic blood pressure was more pronounced than on blood pressure at rest. Parental smoking might be a novel risk factor for higher blood pressure, especially during exercise. In addition, systolic blood pressure during a submaximal exercise test was more closely associated with familial risk factors than was resting blood pressure, even in adolescents.