Magnetic poly(phenylene ethynylene) conjugated microporous polymer microspheres for bactericides enrichment and analysis by ultra-high performance liquid chromatography-tandem mass spectrometry
Magnetic poly(phenylene ethynylene) conjugated microporous polymer microspheres for bactericides enrichment and analysis by ultra-high performance liquid chromatography-tandem mass spectrometry
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磁性聚苯乙炔共轭微孔聚合物微球用于超高效液相色谱-串联质谱富集和分析杀菌剂
DOI：
10.1016/j.chroma.2018.10.043
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发表时间：
2018-12-14
影响因子：
4.1
通讯作者：
Li, Gongke
中科院分区：
文献类型：
--
作者：
Lei, Haoyu;Hu, Yuling;Li, Gongke
新型多功能杀菌剂残留富集材料具有广泛的应用前景。在杀菌剂分析中，很少有材料能同时实现简便的分离、回收和痕量富集。因此，本文报道了一种具有三维网络结构和共价内嵌Fe3O4纳米粒子的磁性聚（苯乙烯-乙炔）共轭微孔聚合物（CMP）微球。密实的聚苯-乙炔框架结构增强了其共轭体系，可以通过IT-IT叠加吸附苯基结构的杀菌剂。由于包埋的Fe3O4纳米颗粒具有超顺磁性，材料可以方便地从样品基体中分离出来并回收。通过对提取和解吸条件的响应面优化，建立了超高效液相色谱-串联质谱（UPLC-MS/MS）联用测定6种微量杀菌剂的方法。检出限为0.27 ~ 3.1 ng / L，在蔬菜水果中检出的杀菌剂浓度为0.038 ~ 0.62 μ g/kg。最后，应用该方法分析了自然条件下杀菌剂耗散的回归方程。研究了蔬菜水果在清洗过程中不同处理的效果，寻求最佳的清洗方法。结果表明，基于磁性CMP的分析方法可实现方便的分离、回收和痕量富集，对实际样品中更多苯基农药的痕量分析具有很大的潜力。(C) 2018 Elsevier B.V.版权所有
The novel multifunction materials for bactericides residue enrichment is attractive. Few materials used in bactericides analysis could simultaneously achieve convenient separation, recycling and trace enrichment. Therefore, a magnetic poly (phenylene ethynylene) conjugated microporous polymer (CMP) microspheres with three-dimensional network structure and covalently built-in Fe3O4 nanoparticles was reported. The structure of dense poly (phenylene ethynylene) frameworks would enhance its conjugation system, which could adsorb bactericides with phenyl structure through IT-IT stacking. The material could be separated from sample matrix conveniently and recycled due to the super paramagnetism from embedded Fe3O4 nanoparticles. After response surface optimization on extraction and desorption conditions, a method for trace analysis of six bactericides determination was developed by collaborative use of ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The detection limits were in the range of 0.27-3.1 ng / L, and bactericides had been found in vegetables and fruits at concentration among 0.038-0.62 mu g/kg. Finally, the method was further applied to analyze the regression equations of bactericide dissipation under natural condition. Effects of different treatment during cleaning process of vegetables and fruits were investigated to seek for the optimal cleaning method. The results revealed that the analytical method based on magnetic CMP which could achieve convenient separation, recycling and trace enrichment, having a great potential for trace analysis of more phenyl pesticides from real samples. (C) 2018 Elsevier B.V. All rights reserved.