Young inversion with multiple linked QTLs under selection in a hybrid zone.
Young inversion with multiple linked QTLs under selection in a hybrid zone.
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DOI:
10.1038/s41559-017-0119
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发表时间:
2017-04-03
影响因子:
16.8
通讯作者:
Mitchell-Olds T
中科院分区:
文献类型:
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作者:
Lee CR;Wang B;Mojica JP;Mandáková T;Prasad KVSK;Goicoechea JL;Perera N;Hellsten U;Hundley HN;Johnson J;Grimwood J;Barry K;Fairclough S;Jenkins JW;Yu Y;Kudrna D;Zhang J;Talag J;Golser W;Ghattas K;Schranz ME;Wing R;Lysak MA;Schmutz J;Rokhsar DS;Mitchell-Olds T
Fixed chromosomal inversions can reduce gene flow and promote speciation in two ways: by suppressing recombination and by carrying locally favored alleles at multiple loci. However, it is unknown whether favored mutations slowly accumulate on older inversions or if young inversions spread because they capture preexisting adaptive Quantitative Trait Loci (QTLs). By genetic mapping, chromosome painting and genome sequencing we have identified a major inversion controlling ecologically important traits in Boechera stricta. The inversion arose since the last glaciation and subsequently reached local high frequency in a hybrid speciation zone. Furthermore, the inversion shows signs of positive directional selection. To test whether the inversion could have captured existing, linked QTLs, we crossed standard, collinear haplotypes from the hybrid zone and found multiple linked phenology QTLs within the inversion region. These findings provide the first direct evidence that linked, locally adapted QTLs may be captured by young inversions during incipient speciation.
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影响因子:
3.7
作者:
Chapman JA;Ho I;Sunkara S;Luo S;Schroth GP;Rokhsar DS
通讯作者:
Rokhsar DS
DOI:
10.1111/j.1558-5646.2010.01175.x
发表时间:
2011-03
期刊:
Evolution; international journal of organic evolution
影响因子:
--
作者:
Anderson JT;Lee CR;Mitchell-Olds T
通讯作者:
Mitchell-Olds T
影响因子:
1.2
作者:
Cingolani, Pablo;Platts, Adrian;Ruden, Douglas M.
通讯作者:
Ruden, Douglas M.
影响因子:
4.5
作者:
Corbett-Detig, Russell B.;Hartl, Daniel L.
通讯作者:
Hartl, Daniel L.
影响因子:
30.8
作者:
通讯作者:
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