DENGUE EPIDEMIC IN THE STATE OF RIO-DE-JANEIRO, BRAZIL, 1990-1 - CO-CIRCULATION OF DENGUE-1 AND DENGUE-2 SEROTYPES
DENGUE EPIDEMIC IN THE STATE OF RIO-DE-JANEIRO, BRAZIL, 1990-1 - CO-CIRCULATION OF DENGUE-1 AND DENGUE-2 SEROTYPES
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DOI：
10.1017/s0950268800056788
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发表时间：
1993-08-01
影响因子：
4.2
通讯作者：
SCHATZMAYR, HG
中科院分区：
文献类型：
--
作者：
NOGUEIRA, RMR;MIAGOSTOVICH, MP;SCHATZMAYR, HG
在1990年和1991年期间，巴西里约热内卢州发现了登革热。它发生在两个流行波;一个是从1990年1月至8月，主要由登革病毒1型（DEN-1）引起，另一个是从1990年10月至1991年5月，由2型病毒（DEN-2）引起。在2109/5964例（35- 4%）病例中，通过病毒分离和/或IgM捕获酶联免疫吸附试验（MAC-ELISA）证实了登革热。从180例患者中分离到DEN-2病毒。HAI试验表明，这些先前感染DEN-1的人中有130人（72%）发生过感染。该流行病被归类为登革热，但严重甚至致命的病例与继发感染有关。
During 1990 and 1991, dengue fever was detected in the State of Rio de Janeiro, Brazil. It occurred in two epidemic waves; one, from January to August 1990, caused predominantly by dengue virus type 1 (DEN-1) the other from October 1990 to May 1991 caused by type 2 virus (DEN-2). Dengue was confirmed by virus isolation and/or IgM capture enzyme-linked immunosorbent assay (MAC-ELISA) in 2109/5964 (35-4 %) of the cases. DEN-2 virus was isolated from 180 patients. HAI tests indicated that of these previous infection with DEN-1 had occurred in 130 (72 %). The epidemic was classified as dengue fever, but severe and even fatal cases occurred in association with secondary infection.