Impact of binocular integrated visual field defects on healthy related quality of life in glaucoma.
Impact of binocular integrated visual field defects on healthy related quality of life in glaucoma.
复制标题
双眼综合视野缺损对青光眼健康相关生活质量的影响
DOI：
10.1097/md.0000000000024069
复制
发表时间：
2021-01-15
期刊：
影响因子：
1.6
通讯作者：
Zhong H
中科院分区：
文献类型：
--
作者：
Zhao C;Li J;Cun Q;Tao Y;Yang W;Tighe S;Zhu Y;Zhong H
摘要探讨不同类型的双眼整合视野缺损对青光眼患者生活质量的影响。将96例原发性青光眼患者按双眼整合视野（BVF）缺损类型分为5组，每组25例，24例，11例，15例，21例。BVF分组标准分别为双眼轻度视野缺损、1眼轻度视野缺损而另眼中度或重度视野缺损、双眼中度和非重叠视野缺损、双眼重叠和中度视野缺损、双眼重度视野缺损。视野（VF）评价基于H-P-A视野分级系统。对入组患者进行视力、视野检查和青光眼生活质量-15问卷（GQL-15），并整合双眼视野结果。比较5组患者视野指数值和生活质量评分的变化及相关性。对影响青光眼患者生活质量的主要因素进行多元回归分析。A组双眼综合视野指数（BVFI）最佳，生活质量最佳。B组BVFI优于C组和D组，但周边视觉眩光和暗适应较差。在BVFI方面，C组和D组之间没有观察到显著差异。C组眩光和暗适应均优于D组。E组BVFI最低，生活质量最差。总的来说，BVFI和分贝（dB）值与GQL-15评分呈负相关，与患者的生活质量呈正相关。双眼综合视野能较准确地反映青光眼患者的视功能。较高的双眼综合视野指数代表青光眼患者较好的生活质量。轻度至中度的同步或互补性双眼VF缺陷对生活质量有轻微影响，而严重和非代偿性VF丧失对青光眼患者的生活质量有显著影响。
Abstract To investigate the impact of different types of binocular integrated visual field defects on the quality of life in glaucoma. Ninety-six patients with primary glaucoma were divided into 5 groups with 25, 24, 11, 15, and 21 patients according to types of the binocular integrated visual field (BVF) defects. The criteria for BVF grouping included mild visual field defect in binocular eyes, mild visual field defect in 1 eye and moderate or advanced defect in the other, moderate and non-overlapping visual field defect in both eyes, overlapping and moderate visual field defect in binocular eyes, and severe defect in both eyes, respectively. The visual field (VF) evaluation was based on H-P-A visual field grading system. Visual acuity, visual field tests and Glaucoma Quality of Life-15 Questionnaire (GQL-15) were performed for enrolled patients, and binocular visual field results were integrated. The changes and correlations of the Visual field index values and quality of life scores were compared among the 5 groups. The main factors affecting the quality of life in glaucoma were analyzed by multiple regression analysis. The best binocular integrated visual field index (BVFI) and optimal quality of life were observed in group A. The BVFI of group B was better than that of group C or group D, but the peripheral vision glare and dark adaptation were worse. No significant difference was noted between group C and group D in terms of BVFI. However, the glare and dark adaptation in group C were better than that in group D. The BVFI was the lowest and the quality of life was the worst in group E. In all, BVFI and decibels (dB) values were negatively correlated with GQL-15 scores and positively correlated with patients’ quality of life. Binocular integrated visual field accurately reflects the visual function in glaucoma. Higher binocular integrated visual field indices represent a better quality of life for patients with glaucoma. Mild to moderate synchronous or complementary binocular VF defects had a slight effect on the quality of life, while severe and non-compensated VF loss significantly impacts on quality of life in glaucoma patients.