Peripheral nerve stimulation characteristics of an asymmetric head-only gradient coil compatible with a high-channel-count receiver array.

Peripheral nerve stimulation characteristics of an asymmetric head-only gradient coil compatible with a high-channel-count receiver array.
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DOI:
10.1002/mrm.26044
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发表时间:
2016-12
影响因子:
3.3
通讯作者:
Schenck JF
Schenck JF
中科院分区:
医学3区
文献类型:
--
作者:
Lee SK;Mathieu JB;Graziani D;Piel J;Budesheim E;Fiveland E;Hardy CJ;Tan ET;Amm B;Foo TK;Bernstein MA;Huston J 3rd;Shu Y;Schenck JF

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旨在表征与商用高通道数仅接收阵列兼容的非对称仅头部梯度线圈的外周神经刺激(PNS)。构建了两个内径为42 cm的非对称头部梯度线圈组原型,用于在3 T下进行脑成像,最大性能规格高达85 mT/m和708 T/m/s。对24名志愿者进行了测试,以测量两种原型的横向(X,左/右; Y,前/后)梯度线圈的PNS阈值。在第二个原型中,还对14名志愿者进行了Z梯度PNS测试,并在PNS测试后立即使用高转换速率EPI进行额外扫描。对于两种原型,Y梯度PNS阈值明显高于X梯度。Z梯度阈值介于X和Y线圈之间。在24名志愿受试者中,只有2名在80 mT/m、500 T/m/s下经历了Y梯度PNS。当读出方向设置为A/P时,所有志愿者都进行了EPI扫描,而没有PNS。测量的非对称头部仅梯度线圈原型的PNS特性表明,这种线圈,特别是在A/P方向,可用于高性能神经成像扫描中的快速EPI读出,与传统的全身梯度线圈相比,PNS问题大大减少。
To characterize peripheral nerve stimulation (PNS) of an asymmetric head-only gradient coil that is compatible with a commercial high-channel-count receive-only array. Two prototypes of an asymmetric head-only gradient coil set, with 42-cm inner diameter, were constructed for brain imaging at 3T with maximum performance specifications of up to 85 mT/m and 708 T/m/s. 24 volunteer tests were performed to measure PNS thresholds with the transverse (X, left/right; Y, anterior/posterior) gradient coils of both prototypes. 14 volunteers were also tested for the Z-gradient PNS in the second prototype, and were additionally scanned with high-slew-rate EPI immediately after the PNS tests. For both prototypes, the Y-gradient PNS threshold was markedly higher than the X-gradient. The Z-gradient threshold was intermediate between those for the X- and Y-coils. Out of the 24 volunteer subjects, only two experienced Y-gradient PNS at 80 mT/m, 500 T/m/s. All volunteers underwent the EPI scan without PNS when the readout direction was set to A/P. Measured PNS characteristics of asymmetric head-only gradient coil prototypes indicate that such coils, especially in the A/P direction, can be used for fast EPI readout in high-performance neuroimaging scans with substantially reduced PNS concerns compared to conventional whole-body gradient coils.