Awareness, accuracy, and predictive validity of self-reported cholesterol in women.

Awareness, accuracy, and predictive validity of self-reported cholesterol in women.
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女性自我报告胆固醇的认知度、准确性和预测有效性。

DOI:
10.1007/s11606-007-0144-1
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发表时间:
2007-05
影响因子:
5.7
通讯作者:
Glynn, Robert J.
Glynn, Robert J.
中科院分区:
医学2区
文献类型:
--
作者:
Huang, Peng-yun A.;Buring, Julie E.;Ridker, Paul M.;Glynn, Robert J.

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虽然目前的指南强调胆固醇知识的重要性,但对这种知识的准确性,影响准确性的因素以及自我报告的胆固醇与心血管疾病(CVD)的关系知之甚少。在妇女健康研究中,39,876名先前没有CVD的女性卫生专业人员被要求提供自我报告和测量的总胆固醇和高密度脂蛋白(HDL)胆固醇水平。人口统计学和心血管危险因素被认为是知晓率和准确性的决定因素。通过报告的胆固醇和测量的胆固醇之间的差异评价准确度。此外,我们研究了10年来自我报告的胆固醇与CVD事件的关系。与不知道自己胆固醇水平的女性相比,有意识的女性(84%)有更高的收入,教育和锻炼水平,更有可能已婚,体重正常,接受高血压和高胆固醇血症治疗,不吸烟,适度饮酒和激素治疗。女性低估了他们的总胆固醇9.7 mg/dL(95% CI:9.2-10.2);协变量几乎不能解释这种差异(R2 < .01)。自我报告的胆固醇水平较高与CVD风险增加密切相关,这发生在741名女性中(风险比1.23/40 mg/dL胆固醇,95% CI:1.15-1.33)。与胆固醇正常的女性相比,胆固醇升高但不知道自己胆固醇水平的女性的风险特别高(HR=1.88,P <0.001)。肥胖、吸烟、未经治疗的高血压或久坐不动的生活方式的妇女对自己的胆固醇水平的认识降低。自我报告的胆固醇低估了测量值,但与CVD密切相关。缺乏对胆固醇升高的认识与CVD风险增加有关。
Although current guidelines emphasize the importance of cholesterol knowledge, little is known about accuracy of this knowledge, factors affecting accuracy, and the relationship of self-reported cholesterol with cardiovascular disease (CVD). The 39,876 female health professionals with no prior CVD in the Women’s Health Study were asked to provide self-reported and measured levels of total and high-density lipoprotein (HDL) cholesterol. Demographic and cardiovascular risk factors were considered as determinants of awareness and accuracy. Accuracy was evaluated by the difference between reported and measured cholesterol. In addition, we examined the relationship of self-reported cholesterol with incident CVD over 10 years. Compared with women who were unaware of their cholesterol levels, aware women (84%) had higher levels of income, education, and exercise and were more likely to be married, normal in weight, treated for hypertension and hypercholesterolemia, nonsmokers, moderate drinkers, and users of hormone therapy. Women underestimated their total cholesterol by 9.7 mg/dL (95% CI: 9.2–10.2); covariates explained little of this difference (R2 < .01). Higher levels of self-reported cholesterol were strongly associated with increased risk of CVD, which occurred in 741 women (hazard ratio 1.23/40 mg/dL cholesterol, 95% CI: 1.15–1.33). Women with elevated cholesterol who were unaware of their level had particularly increased risk (HR=1.88, P <. 001) relative to aware women with normal measured cholesterol. Women with obesity, smoking, untreated hypertension, or sedentary lifestyle have decreased awareness of their cholesterol levels. Self-reported cholesterol underestimates measured values, but is strongly related to CVD. Lack of awareness of elevated cholesterol is associated with increased risk of CVD.
DOI: 10.1097/01.gme.0000119982.77837.c4
发表时间: 2004-09-01
影响因子: 2.7
作者:
Brennan, RM;Crespo, CJ;Wactawski-Wende, J
通讯作者: Wactawski-Wende, J
DOI: 10.1001/archinte.157.20.2326
发表时间: 1997-11-10
影响因子: --
作者:
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通讯作者: Luepker, RV
DOI: 10.1016/0895-4356(96)00010-8
发表时间: 1996-05-01
影响因子: 7.2
作者:
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通讯作者: Pearson, TA
DOI: 10.1007/bf03351531
发表时间: 2001-04-01
影响因子: 4
作者:
Harawa, NT;Morgenstern, H;Moore, A
通讯作者: Moore, A
DOI: 10.1089/152460900318911
发表时间: 2000-01-01
期刊: JOURNAL OF WOMENS HEALTH & GENDER-BASED MEDICINE
影响因子: --
作者:
Rexrode, KM;Lee, IM;Buring, JE
通讯作者: Buring, JE