Treatment outcome of maternal phenylketonuria.
Treatment outcome of maternal phenylketonuria.
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产妇苯丙酮尿症的治疗结果。
DOI：
10.1111/j.1442-200x.1988.tb02530.x
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Heiter,W
中科院分区：
文献类型：
--
作者：
Koch,R;Wenz,E;Bauman,C;Friedman,EG;Azen,C;Fishler,K;Heiter,W
Our experience to date with 40 pregnancies in 13 women with hyperphenylalaninemia indicates that to prevent mental retardation in their children, maternal phenylalanine levels of 120–600 umol/L are needed, in addition to a newborn screening program. While treatment results to date are preliminary, it appears that the phenylalanine‐restricted diet is of value and should be instituted as soon as pregnancy is planned by phenylketonuric women. There is much to be learned by study of these women and referral to a collaborating center in the National Maternal PKU Collaborative Study is recommended.
