Analysis of Incidental Gallbladder Cancer in Cholecystectomies
Analysis of Incidental Gallbladder Cancer in Cholecystectomies
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DOI：
10.7759/cureus.5710
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发表时间：
2019-09-20
影响因子：
1.2
通讯作者：
Ayva, Yasar
中科院分区：
文献类型：
--
作者：
Kanlioz, Murat;Ekici, Ugur;Ayva, Yasar
目的：研究胆囊切除术患者偶发性胆囊癌（IGBC）的发生率。方法：回顾性分析2004-2019年接受胆囊切除术的患者记录。对诊断为胆囊癌（GBC）的患者的人口统计信息、术前放射学检查结果、常规组织病理学检查和手术记录进行回顾并记录检查结果。记录 GBC 患者的术前放射学记录，以及术中疑似 GBC 的检查结果（如有）。 结果：2004 年至 2019 年间，共有 6314 例患者接受了胆囊切除术。其中女性5404例（85.59%），男性910例（14.41%）。中位年龄为 47 岁（最小：19，最大：94），平均年龄为 47.28 +/- 14.60 岁。 6314例患者中9例（0.14%）经术后组织病理学检查确诊为GBC。所有 GBC 患者均为女性，平均年龄为 64.33 +/- 11.08 岁。九分之二的 GBC 病例在术前放射学检查结果中被预先诊断为 GBC；其余 7 名 (0.11%) 患有 IGBC，但没有任何术前发现。结论：据报道，亚洲人群的 GBC 发病率较高。土耳其位于亚洲和欧洲的过渡地带。然而，我们研究中的 GBC 发生率仍远低于亚洲出版物报道的发生率。我们认为，我们的结果可能受到主要地中海式饮食和我们进行研究的地区相对较高的社会经济水平的影响。因此，我们建议在GBC高发地区胆囊切除术后常规进行组织病理学检查。
Objective: To study incidental gallbladder cancer (IGBC) incidence in patients who underwent cholecystectomy.Methods: The records of patients who underwent cholecystectomy between 2004-2019 were retrospectively reviewed. The demographic information, preoperative radiological findings of the patients diagnosed with gallbladder cancer (GBC), as a result of routine histopathological examination and operation records, were reviewed and findings were recorded. The preoperative radiological records of the patients with GBC and, if any, findings of GBC suspected during surgery were recorded.Results: Between 2004-2019, a total of 6314 patients underwent cholecystectomy. Of the patients, 5404 (85.59%) were female and 910 (14.41%) were male. The median age was 47 years (min:19, max:94) and the mean age was 47.28 +/- 14.60 years. Nine out of 6314 patients (0.14%) were diagnosed with GBC by postoperative histopathological examination. All patients with GBC were female and their mean age was 64.33 +/- 11.08 years. Two out of nine GBC cases were prediagnosed with GBC in preoperative radiological findings; the remaining seven (0.11%) had IGBC without any preoperative findings.Conclusion: Asian populations are reported to have a higher incidence of GBC. Turkey is located in the transition zone between Asia and Europe. However, the GBC rates in our study remain far below the rates reported in Asian publications. We believe that our results may be affected by the predominantly Mediterranean-type diet and the relatively higher socioeconomic level of the region where we conducted our study. Consequently, we recommend routine histopathological examination after cholecystectomies in regions with a high incidence of GBC.