Differences in relationships of maternal and paternal age at childbirth with body fat distribution in offspring
Differences in relationships of maternal and paternal age at childbirth with body fat distribution in offspring
复制标题
分娩时母亲和父亲年龄与后代体脂肪分布关系的差异。
DOI：
10.1002/ajhb.23143
复制
发表时间：
2018-11-01
影响因子：
2.9
通讯作者：
Zhang, Zheqing
中科院分区：
文献类型：
--
作者：
Liang, Jingjing;Guo, Yangfeng;Zhang, Zheqing
Objectives Although delayed parenthood has been linked to various adverse health outcomes in offspring, little attention has been given to the relationship between an increased parental age at childbirth and fat distribution in offspring. We aimed to determine the relationship between parental age at childbirth and body fat partitioning in Chinese children. Methods Results A total of 463 children (mean age, 8 years; 43% female) were recruited. Dual-energy X-ray absorptiometry was used to determine the fat mass (FM) and percentage of fat mass (%FM) in various areas of the body. Weight and height were measured. The body mass index (BMI) and fat mass index (FMI) were calculated. A questionnaire was used to collect information about parental variables and other confounders. Multiple linear regression analyses suggested that for each additional year of maternal age at delivery, the BMI, FMI, and FM at whole-body, trunk, android, gynoid, and appendicular region increased by 0.115 kg/m(2), 0.076 kg/m(2); 128.4 g, 57.71 g, 10.96 g, 25.07 g, and 67.88 g, respectively, after adjusting for covariates (P = .002-.017). In the analysis of covariance, children of mothers aged >= 31 years exhibited higher BMI, FMI, total-body and segmental FM, compared to those of mothers aged
