Physical activity and survival after cancer diagnosis in men.
Physical activity and survival after cancer diagnosis in men.
复制标题
男性癌症诊断后的体力活动和生存。
DOI：
10.1123/jpah.2011-0257
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发表时间：
2014
影响因子：
3.1
通讯作者：
Sesso,HowardD
中科院分区：
文献类型：
--
作者：
Lee,I-Min;Wolin,KathleenY;Freeman,SarahE;Sattlemair,Jacob;Sesso,HowardD
BackgroundThe癌症幸存者的数量正在迅速增加，但是，很少有人知道是否从事体力活动后，癌症诊断与死亡率较低的men.MethodsWe进行了一项前瞻性队列研究的1021名男子（平均年龄，71. 3岁）被诊断为癌症（非黑色素瘤皮肤癌）。男性在1988年的问卷调查中报告了他们的身体活动（步行，爬楼梯，参加体育和娱乐活动），平均时间为癌症诊断后6年。体力活动在1993年更新，男性随访至2008年，死亡率随访> 99%，期间有777名男性死亡结果在多因素分析中，与支出相关的全因死亡的相对危险度分别为< 2100，2100-4199，4200-8399，8400- 12599和≥ 12,600 kJ/周的体力活动分别为1.00（参考）、0.77、0.74、0.76和0.52（P趋势< 0.0001）。较高水平的体力活动也与癌症和心血管疾病的死亡率较低（P-趋势= 0.01和0.002，分别）。
BackgroundThe number of cancer survivors is increasing rapidly; however, little is known about whether engaging in physical activity after a cancer diagnosis is associated with lower mortality rates in men.MethodsWe conducted a prospective cohort study of 1021 men (mean age, 71.3 years) who were diagnosed with cancer (other than nonmelanoma skin cancer). Men reported their physical activities (walking, stair climbing, and participation in sports and recreational activities) on questionnaires in 1988, a median of 6 years after their cancer diagnosis. Physical activity was updated in 1993 and men were followed until 2008, with mortality follow-up > 99% complete, during which 777 men died (337 from cancer, 190 from cardiovascular disease).ResultsIn multivariate analyses, the relative risks for all-cause mortality associated with expending < 2100, 2100–4199, 4200–8399, 8400–12,599, and ≥ 12,600 kJ/week in physical activity were 1.00 (referent), 0.77, 0.74, 0.76, and 0.52, respectively (P-trend < 0.0001). Higher levels of physical activity also were associated with lower rates of death from cancer and cardiovascular disease (P-trend = 0.01 and 0.002, respectively).ConclusionsEngaging in physical activity after cancer diagnosis is associated with better survival among men.