Population prevalence of reported and unreported HIV and related behaviors among the household adult population in New York City, 2004
Population prevalence of reported and unreported HIV and related behaviors among the household adult population in New York City, 2004
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DOI：
10.1097/qad.0b013e3282f2ef58
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发表时间：
2008-01-11
期刊：
影响因子：
3.8
通讯作者：
Thorpe, Lorna E.
中科院分区：
文献类型：
--
作者：
Nguyen, Trang Quyen;Gwynn, R. Charon;Thorpe, Lorna E.
背景资料：HIV的监测可能低估了一般人群的感染情况：据估计，25%的美国居民不知道自己感染了HIV。目的：确定纽约市（NYC）成年人HIV感染率和危险行为，并与监测结果进行比较。方法：纽约市健康和营养检查调查（HANES）提供了第一个机会来估计纽约市成年人中基于人口的艾滋病毒流行率。2004年，在20岁以上的成年人中进行了一次代表性抽样调查。以前报告的艾滋病毒感染是从纽约市艾滋病毒/艾滋病监测登记处确定的。对1626名NYC HANES参与者的存档血液样本进行了盲法HIV血清调查。数据被用来估计艾滋病毒感染，未报告的感染，高风险的活动，和自我感知的risk.Results的患病率：总体而言，18.1%从事一个或多个危险的性/针头使用行为，其中92.2%认为自己在低或没有艾滋病毒或其他性传播疾病的风险。21例患者发生HIV（患病率1.4%; 95%置信区间（CI），0.8-2.5）; 1例感染（5%; 95% CI，0.7-29.9）之前未报告，可能未诊断。单纯疱疹病毒2型感染者（4%）、男男性行为者（14%）和针具使用者（21%）的HIV感染率显著升高（P < 0.01）。未报告的艾滋病毒比例低于全国估计数，但调查结果受到样本规模的限制。大多数有危险行为的成年人认为自己的风险很小，这突出了降低风险和常规艾滋病毒筛查的必要性。(c)2008年威科健康垂直酒吧利平科特威廉姆斯&威尔金斯。
Background: Surveillance for HIV likely underestimates infection among the general population: 25% of US residents are estimated to be unaware of their HIV infection.Objective: To determine the prevalence of HIV infection and risk behaviors among New York City (NYC) adults and compare these with surveillance findings.Methods: The NYC Health and Nutrition Examination Survey (HANES) provided the first opportunity to estimate population-based HIV prevalence among NYC adults. It was conducted in 2004 among a representative sample of adults > 20 years. Previously reported HIV infection was identified from the NYC HIV/AIDS Surveillance Registry. A blinded HIV serosurvey was conducted on archived blood samples of 1626 NYC HANES participants. Data were used to estimate prevalence for HIV infection, unreported infections, high-risk activities, and self-perceived risk.Results: Overall, 18.1% engaged in one or more risky sexual/needle-use behaviors, of which 92.2% considered themselves at low or no risk of HIV or another sexually transmitted disease. HIV occurred in 21 individuals (prevalence 1.4%; 95% confidence interval (CI), 0.8-2.5]; one infection (5%; 95% CI, 0.7-29.9) was not reported previously and possibly undiagnosed. HIV infection was significantly elevated in those with herpes simplex virus 2 (4%), men who have sex with men (14%), and needle-users (21%) (P < 0.01).Conclusions: Among NYC adults, HIV prevalence was consistent with surveillance findings overall. The proportion of unreported HIV was less than estimated nationally, but findings were limited by sample size. Most adults with risky behaviors perceived themselves to be at minimal risk, highlighting the need for risk reduction and routine HIV screening. (c) 2008 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.