The Engelbreth-Holm-Swarm mouse tumor produces undersulfated heparan sulfate and oversulfated galactosaminoglycans.

The Engelbreth-Holm-Swarm mouse tumor produces undersulfated heparan sulfate and oversulfated galactosaminoglycans.
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Engelbreth-Holm-Swarm 小鼠肿瘤产生低硫酸化的硫酸乙酰肝素和高硫酸化的半乳糖胺聚糖。

DOI：
10.1016/0006-291x(89)91980-3
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发表时间：
1989
期刊：
Biochemical and biophysical research communications
影响因子：
3.1
通讯作者：
I. Yamashina
I. Yamashina
中科院分区：
生物学4区
文献类型：
--
作者：
K. Sugahara;Yutaka Okumura;I. Yamashina

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Glycosaminoglycans were prepared from the Engelbreth-Holm-Swarm mouse tumor. Enzymatic analysis demonstrated heparan sulfate (95.8%) and chondroitinase ABC-sensitive galactosaminoglycans (4.2%). HPLC analysis of the disaccharide units showed that heparan sulfate chains were undersulfated on average, comprizing approximately 30% nonsulfated and 60% N-sulfated disaccharide units with small proportions of other monosulfated and disulfated disaccharide units. In contrast, galactosaminoglycan chains were oversulfated, containing an appreciable proportion (15%) of a 4,6-disulfated (so-called E-type) disaccharide unit in addition to 51% of a 4-sulfated, 22% of a 6-sulfated, and 11% of a nonsulfated disaccharide unit. The significance of the oversulfated disaccharide structure is discussed in relation to the possible regulation of functions of hybrid proteoglycans from which the galactosaminolycan chains are derived.
Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfate.
DOI： 10.1016/s0021-9258(18)34561-7
发表时间： 1982-06
期刊： The Journal of biological chemistry
影响因子： --
作者：
E. Razin;R. Stevens;F. Akiyama;K. Schmid;K. Austen
通讯作者： E. Razin;R. Stevens;F. Akiyama;K. Schmid;K. Austen
Secretory granules of heparin-containing rat serosal mast cells also possess highly sulfated chondroitin sulfate proteoglycans.
含肝素的大鼠浆膜肥大细胞的分泌颗粒也具有高度硫酸化的硫酸软骨素蛋白聚糖。
DOI： --
发表时间： 1986
期刊： The Journal of biological chemistry
影响因子： --
作者：
Katz,HR;Austen,KF;Caterson,B;Stevens,RL
通讯作者： Stevens,RL
Structural studies on sulfated glycopeptides from the carbohydrate-protein linkage region of chondroitin 4-sulfate proteoglycans of swarm rat chondrosarcoma. Demonstration of the structure Gal(4-O-sulfate)beta 1-3Gal beta 1-4XYL beta 1-O-Ser.
鼠群软骨肉瘤软骨素 4-硫酸盐蛋白聚糖碳水化合物-蛋白质连接区硫酸化糖肽的结构研究。
DOI： --
发表时间： 1988
期刊： The Journal of biological chemistry
影响因子： --
作者：
Sugahara,K;Yamashina,I;DeWaard,P;VanHalbeek,H;Vliegenthart,JF
通讯作者： Vliegenthart,JF
The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans.
来自小鼠乳腺上皮细胞的细胞表面蛋白聚糖含有硫酸软骨素和硫酸乙酰肝素糖胺聚糖。
DOI： --
发表时间： 1985
期刊： The Journal of biological chemistry
影响因子： --
作者：
Rapraeger,A;Jalkanen,M;Endo,E;Koda,J;Bernfield,M
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Structural analysis of the asparagine-linked oligosaccharides from three lysosomal enzymes of Dictyostelium discoideum. Evidence for an unusual acid-stable phosphodiester.
盘基网柄菌三种溶酶体酶的天冬酰胺连接寡糖的结构分析。
DOI： --
发表时间： 1983
期刊： The Journal of biological chemistry
影响因子： --
作者：
Freeze,HH;Yeh,R;Miller,AL;Kornfeld,S
通讯作者： Kornfeld,S